醉酒患者的创伤性脑损伤

Traumatic brain injury in intoxicated patients.

作者信息

Golan Jeff Dror, Marcoux Judith, Golan Eyal, Schapiro Robert, Johnston Karen M, Maleki Mahammed, Khetarpal Suneel, Jacques Line

机构信息

Department of Neurosurgery, Montreal Neurological Hospital and the Montreal General Hospital, McGill University, Montreal, Canada.

出版信息

J Trauma. 2007 Aug;63(2):365-9. doi: 10.1097/TA.0b013e31811ec178.

DOI:10.1097/TA.0b013e31811ec178

PMID:17693837

Abstract

BACKGROUND

We sought to evaluate the effect alcohol intoxication may have had in nonsurgically treated patients with severe traumatic brain injury.

METHODS

The Montreal General Hospital Traumatic Brain Injury Registry was used to identify all adult patients with a Glasgow Coma Scale score < or =8 at admission, within a 15-month period. All charts were retrospectively reviewed.

RESULTS

Twenty-three patients had toxic blood alcohol levels (BAL > or =21.7 mmol/L), 24 were alcohol negative (BAL <3 mmol/L), and 10 were alcohol-influenced or had unknown BAL. Patients were more likely to have intracranial pressure monitoring if they had multiple intracranial hemorrhages, sustained multiple injuries, or had a post-resuscitative Glasgow Coma Scale score < or =8. Intoxicated patients had a mean delay of 151 minutes more in the insertion time of an intracranial pressure monitoring device, compared with alcohol-negative patients.

CONCLUSIONS

Alcohol was a confounding factor in the treatment of some of our patients.

摘要

背景

我们试图评估酒精中毒对非手术治疗的重型颅脑损伤患者可能产生的影响。

方法

利用蒙特利尔综合医院颅脑损伤登记处的数据，在15个月的时间内，确定所有入院时格拉斯哥昏迷量表评分≤8分的成年患者。对所有病历进行回顾性审查。

结果

23例患者血液酒精水平达到中毒标准（血液酒精含量≥21.7 mmol/L），24例酒精检测呈阴性（血液酒精含量<3 mmol/L），10例受酒精影响或血液酒精含量不明。如果患者有多处颅内出血、多处受伤或复苏后格拉斯哥昏迷量表评分≤8分，则更有可能接受颅内压监测。与酒精检测呈阴性的患者相比，酒精中毒患者颅内压监测装置的插入时间平均延迟151分钟。