Marshall Brandon D L, Wood Evan, Li Kathy, Kerr Thomas
British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, BC, Canada.
J Acquir Immune Defic Syndr. 2007 Oct 1;46(2):248-52. doi: 10.1097/QAI.0b013e31814a5533.
Despite efforts to scale up HIV prevention services for drug users, high rates of HIV risk behavior persist among some subpopulations. Given that few prospective studies have considered the relationship between sexual activity and syringe sharing, we sought to evaluate syringe sharing among male injection drug users (IDUs) who have sex with men (MSM) in Vancouver.
We performed a longitudinal analysis of factors associated with syringe borrowing among male participants enrolled in the Vancouver Injection Drug Users Study during the years 1996 to 2005 using generalized estimating equations (GEE).
Among the 1019 male participants included in this analysis, 553 (54.3%) reported borrowing syringes during the study period. In multivariate GEE analysis, MSM were at an elevated risk for syringe borrowing (adjusted odds ratio [AOR] = 1.50, 95% confidence interval [CI]: 1.10 to 2.04) after extensive adjustment for other known risk factors.
Among male participants, having sex with men was found to be strongly and independently associated with syringe borrowing. Our findings may aid policy makers in their efforts to identify IDUs who should be targeted with education and prevention efforts, and indicate the need for ongoing development of prevention interventions that address sexual orientation.
尽管已努力扩大针对吸毒者的艾滋病毒预防服务,但某些亚人群中艾滋病毒风险行为的高发生率仍然存在。鉴于很少有前瞻性研究考虑过性活动与共用注射器之间的关系,我们试图评估温哥华与男性发生性行为的男性注射吸毒者(IDU)中的注射器共用情况。
我们使用广义估计方程(GEE)对1996年至2005年期间参加温哥华注射吸毒者研究的男性参与者中与借用注射器相关的因素进行了纵向分析。
在纳入该分析的1019名男性参与者中,553人(54.3%)报告在研究期间借用过注射器。在多变量GEE分析中,在对其他已知风险因素进行广泛调整后,与男性发生性行为的男性借用注射器的风险升高(调整后的优势比[AOR]=1.50,95%置信区间[CI]:1.10至2.04)。
在男性参与者中,发现与男性发生性行为与借用注射器密切且独立相关。我们的研究结果可能有助于政策制定者努力确定应接受教育和预防努力的注射吸毒者,并表明需要持续开展针对性取向的预防干预措施。