L-色氨酸诱导的嗜酸性粒细胞增多性肌痛综合征。I. 两例伴有弹性假黄瘤样皮肤改变的病例报告。
L-tryptophan-induced eosinophilia-myalgia syndrome. I. Report of two cases with pseudoxanthoma-elasticum-like skin changes.
作者信息
Mainetti C, Schmied E, Masouyé I, Chavaz P, Saurat J H
机构信息
Department of Dermatology, Hôpital Cantonal Universitaire, Geneva, Switzerland.
出版信息
Dermatologica. 1991;183(1):57-61.
Two female patients who fulfilled the criteria for L-tryptophan-induced eosinophilia-myalgia syndrome (EMS) had, together with morphea-like and fasciitis-like sclerotic changes of the skin, lesions that clinically mimicked pseudoxanthoma elasticum (PXE). Histology was compatible with the diagnosis; electron microscopy did not reveal calcium deposits. PXE-like changes may represent an additional feature of the pleomorphic L-tryptophan-induced EMS.
两名符合L-色氨酸诱导的嗜酸性粒细胞增多性肌痛综合征（EMS）标准的女性患者，除了皮肤出现硬斑病样和筋膜炎样硬化改变外，还有临床上酷似弹性假黄瘤（PXE）的损害。组织学检查符合诊断；电子显微镜检查未发现钙沉积。PXE样改变可能是多形性L-色氨酸诱导的EMS的另一个特征。
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