Bogers J P A M
High Care van GGZ Haagstreek, onderdeel van Rivierduinen, te Leidschendam.
Tijdschr Psychiatr. 2007;49(8):575-9.
This article describes four patients using clozapine, with neutropenia. Clozapine-induced neutropenia can be one of three types: pseudo, benign or malignant. The malignant type can give cause for serious concern; in that case treatment with clozapine must be stopped. Pseudo-neutropenia and benign neutropenia, however, occur frequently. In these cases it is probably unnecessary to stop clozapine medication, particularly if clozapine is clearly indicated.
本文描述了4例使用氯氮平且出现中性粒细胞减少症的患者。氯氮平所致中性粒细胞减少症可分为三种类型:假性、良性或恶性。恶性类型可能会引起严重关注;在这种情况下,必须停用氯氮平治疗。然而,假性中性粒细胞减少症和良性中性粒细胞减少症较为常见。在这些情况下,可能无需停用氯氮平药物,尤其是在氯氮平有明确指征时。