Hessel V, Löb P, Krtschil U, Löwe H
Department of Chemical Engineering and Chemistry, Eindhoven University of Technology, STW 1.35, PO Box 513, 5600 MB Eindhoven, The Netherlands.
Ernst Schering Found Symp Proc. 2006(3):205-40. doi: 10.1007/2789_2007_035.
The true potential of microprocess technology for process intensification is not yet fully clear and needs to be actively explored, although more and more industrial case stories provide information. This paper uses a shortcut cost analysis to show the major cost portions for processes conducted by microstructured reactors. This leads to predicting novel chemical protocol conditions, which are tailored for microprocess technology and which are expected to highly intensify chemical processes. Some generic rules to approach this are termed new process windows, because they constitute a new approach to enabling chemistry. Using such process intensification together with scaled-out microstructured reactors, which is demonstrated by the example of gas-liquid microprocessing, paves the road to viable industrial microflow processes. Several such commercially oriented case studies are given. Without the use of new process windows conditions, microprocess technology will probably stick to niche applications.
尽管越来越多的工业案例提供了相关信息，但微加工技术在过程强化方面的真正潜力尚未完全明晰，仍需积极探索。本文采用一种简化成本分析方法，以展示微结构化反应器所进行过程的主要成本部分。这进而促成了对新型化学工艺条件的预测，这些条件是为微加工技术量身定制的，有望极大地强化化学过程。一些实现这一目标的通用规则被称为新的工艺窗口，因为它们构成了一种实现化学过程的新方法。将这种过程强化与放大的微结构化反应器相结合（以气液微加工为例进行了演示），为可行的工业微流过程铺平了道路。文中给出了几个此类面向商业的案例研究。如果不采用新的工艺窗口条件，微加工技术可能仍局限于小众应用。
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