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[产褥期重度子痫前期的管理。硝苯地平舌下含服与肼屈嗪的对比研究]

[Management of severe pre-eclampsia in the puerperium. Comparative study of sublingual nifedipine and hydralazine].

作者信息

Walss Rodríguez R J, Villarreal Ordaz F

机构信息

Centro Médico Nacional Torreón, IMSS, Coah.

出版信息

Ginecol Obstet Mex. 1991 Jul;59:207-10.

PMID:1769603
Abstract

At random, two therapeutic schemes for severe preeclampsia during the puerperium, were evaluated. Group A (n = 20) was left without antihypertensive medication and sublingual nifedipine was used only in case of diastolic pressure of 110 mmHg or more. Group B (n = 18) receive Hydralazine 40 mlg. per os, every 6 hrs.; in this group also, nifedipine was administered in case of diastolic pressure of 110 mmHg or more. The only differences were that in group B the intervals for the administration of nifedipine were much shorter than in group A; also, in the same group the need for another antihypertensive was more frequent (5 of 18 vs 1 of 20 patients).

摘要

随机评估了两种产后重度子痫前期的治疗方案。A组(n = 20)不使用抗高血压药物,仅在舒张压达到110 mmHg及以上时使用舌下硝苯地平。B组(n = 18)口服肼屈嗪40 mg,每6小时一次;在该组中,若舒张压达到110 mmHg及以上也使用硝苯地平。唯一的差异是,B组硝苯地平的给药间隔比A组短得多;此外,同一组中需要使用其他抗高血压药物的情况更频繁(18例中有5例,而20例中有1例)。

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