Device-specific resistance to in vivo displacement of stent-grafts implanted with maximum iliac fixation.

PURPOSE

To compare the in vivo device-specific downward displacement force of various externally supported endografts implanted with maximum iliac fixation.

METHODS

Twenty female sheep had aneurysms created with a graft patch in the infrarenal aorta. In 12 animals, a fully supported modular bifurcated stent-graft [AneuRx (n=4), Talent (n=4), or Zenith (n=4)] was deployed; in the other 8, a bifurcated aortic graft was surgically anastomosed to the infrarenal aorta. All grafts were displaced in vivo by applying downward traction to a guidewire brought out both femoral arteries. The peak force to cause initial stent-graft migration or disruption of the sutured anastomosis was recorded and compared.

RESULTS

There was no difference in animal size, aortic neck diameter or length, aneurysm size, or iliac artery diameter for animals receiving the AneuRx, Talent, or Zenith stent-grafts and those undergoing surgical repair. The mean length of iliac fixation was 31.0+/-0.3 mm, 30.8+/-0.5 mm, and 31.3+/-0.6 mm for the AneuRx, Talent, and Zenith devices, respectively (p=NS). Peak force to initiate migration was 30.2+/-5.5 N (range 25-38) for the AneuRx, 44.8+/-5.6 N (range 40-53) for the Talent, 46.7+/-5.4 N (range 38-55) for the Zenith, and 40.6+/-7.5 N (range 31-50) for the surgical anastomosis (p=0.01). There was no difference detected in the peak force to initiate migration between the suprarenally affixed Talent and Zenith stent-grafts and the surgical anastomosis (p=0.55).

CONCLUSION

Devices with a suprarenal component require significantly greater force to cause downward displacement compared to infrarenal devices. The force required to displace a suprarenal device with maximal iliac fixation was equivalent to the force required to disrupt a surgical anastomosis.