Litchfield K N, Harten J M, Anderson K J, Kinsella J, McGrady E M
Southern General Hospital, Department of Anaesthesia, 1345 Govan Road, Glasgow G51 4TF, UK.
Anaesthesia. 2007 Sep;62(9):931-5. doi: 10.1111/j.1365-2044.2007.05150.x.
Fifteen healthy, full-term women with singleton pregnancies were exposed to an increased F(I)o(2) of 0.4 and their haemodynamic responses measured with a non-invasive transthoracic bio-impedance monitor. There was a mean reduction in cardiac index from 3.18 to 3.03 l x min(-1) x m(-2) (4.7%, p = 0.004). The mean indexed systemic vascular resistance increased from 2049 to 2178 dynes x cm(-5) x m(-2) (5.7%, p = 0.005). There were no significant changes in stroke index, heart rate or mean arterial pressure. This study demonstrates that even a moderate increase in inspired oxygen fraction has significant effects on the cardiovascular system of the term parturient.
15名健康、足月单胎妊娠的女性暴露于40%的吸入氧浓度增加环境中，并用无创经胸生物阻抗监测仪测量其血流动力学反应。心脏指数平均从3.18降至3.03升×分钟-1×米-2（4.7%，p = 0.004）。平均体循环血管阻力指数从2049增至2178达因×厘米-5×米-2（5.7%，p = 0.005）。每搏输出量指数、心率或平均动脉压无显著变化。本研究表明，即使吸入氧分数适度增加也会对足月产妇的心血管系统产生显著影响。
