Kadam U T, Croft P R
Primary Care Sciences Research Centre, Keele University, Staffordshire, UK.
Fam Pract. 2007 Oct;24(5):412-9. doi: 10.1093/fampra/cmm049. Epub 2007 Aug 14.
Multiple chronic conditions occurring in the same individual are associated with adverse health outcomes. In family practice, individuals are seen who, over time, may experience many different symptoms, illnesses and chronic diseases. Measures for defining multimorbidity, which incorporate the diverse range of health problems seen in population-based family practice, remain to be developed. We have investigated whether routinely collected consultation data could be used as the basis for a simple classification of multimorbidity that reflects an individual's overall health status.
Morbidity consultation data for 9,439 English patients aged 50 years and over in an 18-month time period were linked to their self-reported physical health status measured by Short-Form 12 at the end point. Associations between physical function and all-cause multimorbidity counts were estimated relative to single morbidity only, and between physical function and morbidity severity (185 morbidities categorized on four ordinal scales of severity) relative to persons who had not consulted about any of the 185.
In the 18-month period, 19% had consulted for a single morbidity and 23% for six or more (a high multimorbidity count). An estimated 24% of poor physical function in the family practice consulting population may be attributable to high multimorbidity. There was an increasing strength of association between poor physical function and increasing severity of multimorbidity on all four severity scales. Estimated associations (adjusted odds ratios) of the most severe morbidity categories with poor physical function were, for each of the four scales, respectively, 5.6 for chronicity [95% confidence interval (CI) 4.4-7.1], 7.0 for time course (4.5-10.6) and 3.6 for health care use (2.0-6.6) and for patient impact (6.7; 5.2-8.8).
Multimorbidity defined by using routinely collected family practice consultation data and classified by count and by severity was associated with poorer physical function. This approach offers the potential for systematic use of routine records to classify multimorbidity and to identify groups with high likelihood of poor physical status for needs assessment and targeted intervention.
同一个体出现多种慢性病与不良健康结局相关。在家庭医疗中,会接待一些随着时间推移可能经历许多不同症状、疾病和慢性病的个体。用于定义多重疾病的测量方法,应纳入在基于人群的家庭医疗中所见到的各种健康问题,目前仍有待开发。我们研究了常规收集的会诊数据是否可作为反映个体整体健康状况的多重疾病简单分类的基础。
将18个月时间段内9439名年龄在50岁及以上的英国患者的发病会诊数据,与他们在终点时通过简短健康调查问卷12所报告的身体健康状况相联系。相对于仅患有单一疾病的情况,估计身体功能与全因多重疾病计数之间的关联;相对于未就185种疾病中的任何一种进行会诊的人,估计身体功能与疾病严重程度(185种疾病按四个严重程度序数等级分类)之间的关联。
在18个月期间,19%的人因单一疾病进行了会诊,23%的人因六种或更多疾病(高多重疾病计数)进行了会诊。在家庭医疗会诊人群中,估计24%的身体功能不佳可能归因于高多重疾病。在所有四个严重程度等级上,身体功能不佳与多重疾病严重程度增加之间的关联强度都在增加。对于四个等级中的每一个,最严重疾病类别与身体功能不佳的估计关联(调整后的优势比)分别为:慢性为5.6 [95%置信区间(CI)4.4 - 7.1],病程为7.0(4.5 - 10.6),医疗保健使用为3.6(2.0 - 6.6),对患者的影响为6.7(5.2 - 8.8)。
使用常规收集的家庭医疗会诊数据定义并按计数和严重程度分类的多重疾病,与较差的身体功能相关。这种方法为系统利用常规记录对多重疾病进行分类以及识别身体状况不佳可能性高的群体以进行需求评估和有针对性的干预提供了潜力。