Labrecque Joane, Marchand André, Dugas Michel J, Letarte Andrée
Université du Québec à Montréal Hôpital Louis-H Lafontaine, Montréal, Canada.
Behav Modif. 2007 Sep;31(5):616-37. doi: 10.1177/0145445507301132.
The goal of this study was to evaluate the efficacy of cognitive-behavioral therapy for comorbid panic disorder with agoraphobia (PDA) and generalized anxiety disorder (GAD) by combining treatment strategies for both disorders. A single-case, multiple-baseline design across participants was used. Three participants with primary PDA and secondary GAD took part in the study. The efficacy of the treatment was assessed by means of a structured interview, self-administered questionnaires, and daily self-monitoring measures. After treatment, 2 of the 3 participants achieved high end-state functioning and maintained this level of functioning at 3-, 6-, and 12-month follow-ups. The third participant also improved but only reached high end-state functioning at 6-month follow-up. It therefore appears that the combined treatment is relatively effective for PDA-GAD comorbidity. Possible avenues for improving the treatment are suggested.
本研究的目的是通过结合针对两种障碍的治疗策略，评估认知行为疗法对伴有广场恐惧症的惊恐障碍（PDA）和广泛性焦虑障碍（GAD）共病的疗效。采用了跨参与者的单病例、多基线设计。三名原发性PDA和继发性GAD患者参与了研究。通过结构化访谈、自我管理问卷和每日自我监测措施评估治疗效果。治疗后，三名参与者中有两名实现了高水平的终末状态功能，并在3个月、6个月和12个月的随访中维持了这一功能水平。第三名参与者也有所改善，但仅在6个月随访时达到高水平的终末状态功能。因此，联合治疗似乎对PDA-GAD共病相对有效。文中还提出了改善治疗的可能途径。
