Manolescu Andrei R, Witkowska Kate, Kinnaird Adam, Cessford Tara, Cheeseman Chris
Membrane Protein Research Group, Department of Physiology, University of Alberta, Edmonton, Alberta, Canada.
Physiology (Bethesda). 2007 Aug;22:234-40. doi: 10.1152/physiol.00011.2007.
The recent sequencing of the human genome has resulted in the addition of nine new hGLUT isoforms to the SLC2A family, many of which have widely varying substrate specificity, kinetic behavior, and tissue distribution. This review examines some new hypotheses related to the structure and function of these proteins.
最近对人类基因组的测序使得SLC2A家族新增了九种新的hGLUT亚型,其中许多亚型具有广泛不同的底物特异性、动力学行为和组织分布。本综述探讨了与这些蛋白质的结构和功能相关的一些新假说。