Nomiyama R, Nunoi K, Tsutsu N, Satho Y, Yoshizumi H, Himeno H, Nakamura Y, Fujishima M
Second Department of Internal Medicine, Kyushu University, Fukuoka, Japan.
J Diabet Complications. 1991 Apr-Sep;5(2-3):155-6. doi: 10.1016/0891-6632(91)90054-s.
The prevalences and risk factors of micro- and macroalbuminuria were surveyed in all 927 patients with diabetes mellitus who visited outpatient clinics in 27 hospitals in the Fukuoka prefecture on a designated day. The urinary albumin-creatinine ratio (UAI; mg/g Cr) of spot urine was determined in all patients except those with persistent macroproteinuria. The results were as follows: (1) The prevalences of microalbuminuria (UAI 30-299) and macroalbuminuria (UAI greater than or equal to 300) were 26% and 15%, respectively. (2) Hyperglycemia and high blood pressure synergistically increased the prevalences. (3) The independent risk factors of microalbuminuria were severities of retinopathy and neuropathy, duration of diabetes, blood pressure, and HbA1c, as determined by logistic regression analysis, although the explanation rate was low.