从离体灌流大鼠心脏中释放3':5'-环磷酸腺苷。
The release of adenosine 3':5'-cyclic monophosphate from the isolated perfused rat heart.
作者信息
O'Brien J A, Strange R C
出版信息
Biochem J. 1975 Nov;152(2):429-32. doi: 10.1042/bj1520429.
Abstract
Although basal release of cyclic AMP from isolated perfused rat hearts was not measurable, isoprenaline induced substantial release of the nucleotide, suggesting that in vivo the myocardium can contribute to plasma cyclic AMP. Anoxia also increased the amount of cyclic AMP released, but insulin and nicotinate alone or in combination had no effect.
摘要
尽管从离体灌注大鼠心脏中无法检测到环磷酸腺苷（cAMP）的基础释放，但异丙肾上腺素可诱导该核苷酸的大量释放，这表明在体内心肌可对血浆环磷酸腺苷产生影响。缺氧也会增加环磷酸腺苷的释放量，但单独使用胰岛素和烟酸或二者联合使用均无效果。
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