小花鬼针草中的两种新单萜糖苷和一种新的(+)-茉莉酮糖苷

Two new monoterpene glycosides and a new (+)-jasmololone glucoside from Bidens parviflora Willd.

作者信息

Wang Nai-Li, Wang Jue, Yao Xin-Sheng, Kitanaka Susumu

机构信息

Department of Natural Products Chemistry, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, Shenyang 110015, China.

出版信息

J Asian Nat Prod Res. 2007 Apr-Aug;9(3-5):449-55. doi: 10.1080/10286020500532033.

DOI:10.1080/10286020500532033

PMID:17701564

Abstract

Two new monoterpene glycosides named bidensmenthosides A, B and a new (+)-jasmololone glucoside, were isolated from the air-dried whole plant of Bidens parviflora Willd. Their structures were determined as (1S, 3S, 4R)-3-hydroxy-p-menth-6-one 3-O-beta-D-glucopyranoside (1), (3R, 4R)-3-hydroxy-p-menth-1 (2)-en-6-one 3-O-beta-D-glucopyranoside (2) and (4R)-hydroxy-3-methyl-2-(2 Z-pentenyl)-cyclopent-2-enone 4-O-beta-D-glucopyranoside (3) based on spectroscopic analysis and physiochemical properties, respectively. The bidensmenthosides A, B and aglycone of 3 were found to reduce 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radicals.

摘要

从小花鬼针草的干燥全草中分离出两种新的单萜糖苷，命名为鬼针草苷A、B，以及一种新的(+)-茉莉酮醇葡萄糖苷。根据光谱分析和理化性质，它们的结构分别确定为(1S, 3S, 4R)-3-羟基-对薄荷-6-酮3-O-β-D-吡喃葡萄糖苷(1)、(3R, 4R)-3-羟基-对薄荷-1(2)-烯-6-酮3-O-β-D-吡喃葡萄糖苷(2)和(4R)-羟基-3-甲基-2-(2Z-戊烯基)-环戊-2-烯酮4-O-β-D-吡喃葡萄糖苷(3)。发现鬼针草苷A、B和3的苷元能还原2, 2-二苯基-1-苦基肼基(DPPH)自由基。