Rosa Marilin, Chopra Harpreet K, Sahoo Sunati
Cytopathology Section, Department of Pathology and Laboratory Medicine, University of Louisville, Louisville, Kentucky 40202, USA.
Diagn Cytopathol. 2007 Sep;35(9):565-7. doi: 10.1002/dc.20693.
Carcinoma of the prostate is predominantly a disease of older men. Men younger than 50 years of age account for approximately 1% of all patients diagnosed with prostate cancer. Patients generally present with urinary symptoms and rarely with metastatic disease. Lymphatic spread typically occurs to the obturator and internal iliac nodes. We report a case of an aggressive prostate adenocarcinoma in a 47-year-old white male who presented with nausea, vomiting, and enlarged inguinal lymph nodes for 1 month. A fine needle aspiration biopsy (FNAB) and immunohistochemical stains performed on the FNAB revealed metastatic prostatic adenocarcinoma. The initial clinical presentation of inguinal lymphadenopathy, the age of the patient and the cytologic features made this an unusual case.
前列腺癌主要是老年男性的疾病。50岁以下的男性约占所有前列腺癌确诊患者的1%。患者通常表现为泌尿系统症状，很少出现转移性疾病。淋巴转移通常发生至闭孔和髂内淋巴结。我们报告一例47岁白人男性侵袭性前列腺腺癌病例，该患者出现恶心、呕吐及腹股沟淋巴结肿大1个月。细针穿刺活检（FNAB）及对FNAB进行的免疫组化染色显示为转移性前列腺腺癌。腹股沟淋巴结病的初始临床表现、患者年龄及细胞学特征使该病例不同寻常。
