Liu Weimin, Xu Liwei, Sheng Ruilong, Wang Pengfei, Li Huaping, Wu Shikang
Laboratory of Organic Optoelectronic Functional Materials and Molecular Engineering, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100080, China.
Org Lett. 2007 Sep 13;9(19):3829-32. doi: 10.1021/ol701620h. Epub 2007 Aug 17.
Compound 1, a new fluorescent chemosensor signaling via significantly enhanced fluorescence when bound with cation analytes, was synthesized and characterized. This fluorescent chemosensor exhibits its selectivity to Cd2+ among a series of cations in HEPES buffer solution. Its in vitro sensitivity to Cd2+ was demonstrated in the HK-2 cell line with use of confocal microscopy. The mechanistic selectivity and sensitivity of compound 1 to Cd2+ was discussed on the basis of fluorescence, 1H NMR, and mass spectroscopic results.
