Sedberry-Ross S, Stisser B C, Henderson C G, Rushton H G, Belman A B
Children's National Medical Center, Washington, D.C, USA.
J Urol. 2007 Oct;178(4 Pt 2):1663-7. doi: 10.1016/j.juro.2007.03.198. Epub 2007 Aug 17.
We report our 17-year experience using split prepuce in situ onlay hypospadias repair, including long-term followup of the first 100 patients initially reported on in 1998.
We identified 421 patients who underwent in situ onlay repair. Charts were retrospectively reviewed to determine preoperative management, intraoperative details and complications.
In situ onlay repair was used to repair glanular hypospadias in 22 cases (5.2%), coronal hypospadias in 184 (43.7%), distal shaft hypospadias in 152 (36.1%), mid shaft hypospadias in 51 (12.1%), proximal shaft hypospadias in 7 (1.6%) and hypospadias in the penoscrotal region in 5 (1.2%). Repair was successful with 1 procedure in 376 patients (89.4%), which increased to 99.8% after a second procedure. Complications were defined as any problem that gave the surgeon or family reason for concern. Functional complications requiring reoperation occurred in 45 patients (10.6%). Minor complications requiring simple procedures or early postoperative evaluation occurred in 17 patients (4%). Concerns not requiring intervention occurred in 27 patients (6.4%). There were no urethral strictures. Three patients (0.7%) were lost to followup. Repair is pending in 1 patient.
In situ onlay repair preserves the urethral plate and allows the formation of a well vascularized flap with adequate tissue to completely cover the neourethra, resulting in a low rate of major complications. With longer followup, inclusion of more mid shaft repairs and expansion to more proximal degrees of hypospadias our complication rates are higher than previously reported but there have been no urethral strictures in 17 years of experience. Since complications present at a median of 158 days (mean 570) after the procedure, long-term followup is indicated.
我们报告了17年来使用原位包皮瓣镶嵌术修复尿道下裂的经验,包括对1998年首次报告的前100例患者的长期随访。
我们确定了421例行原位镶嵌修复术的患者。回顾病历以确定术前管理、术中细节及并发症情况。
原位镶嵌修复术用于修复龟头型尿道下裂22例(5.2%)、冠状沟型尿道下裂184例(43.7%)、阴茎体远端型尿道下裂152例(36.1%)、阴茎体中段型尿道下裂51例(12.1%)、阴茎体近端型尿道下裂7例(1.6%)以及阴茎阴囊型尿道下裂5例(1.2%)。376例患者(89.4%)一次手术修复成功,二次手术后成功率升至99.8%。并发症定义为任何让外科医生或家属担心的问题。45例患者(10.6%)出现需要再次手术的功能性并发症。17例患者(4%)出现需要简单处理或术后早期评估的轻微并发症。27例患者(6.4%)存在无需干预的问题。无尿道狭窄发生。3例患者(0.7%)失访。1例患者的修复手术尚未进行。
原位镶嵌修复术保留了尿道板,能形成血供良好、有足够组织完全覆盖新尿道的皮瓣,导致严重并发症发生率较低。随着随访时间延长、纳入更多阴茎体中段修复病例以及向更近端程度的尿道下裂扩展,我们的并发症发生率高于先前报告,但17年经验中未出现尿道狭窄情况。由于并发症多在术后中位时间158天(平均570天)出现,因此需要进行长期随访。