Mphande A N G, Killowe C, Phalira S, Jones H Wynn, Harrison W J
Beit Cure International Hospital, Blantyre, Malawi.
J Wound Care. 2007 Jul;16(7):317-9. doi: 10.12968/jowc.2007.16.7.27053.
To investigate whether there is a difference between the efficacy of honey and sugar as wound dressings.
Patients with open or infected wounds were randomised to receive either honey or sugar dressings. Bacterial colonisation, wound size, wound ASEPSIS score and pain were assessed at the start of treatment and at weekly intervals until full healing occurred.
Forty patients were enrolled; 18 received sugar dressings and 22 honey dressings. In the honey group, 55% of patients had positive wound cultures at the start of treatment and 23% at one week, compared with 52% and 39% respectively in the sugar group.The median rate of healing in the first two weeks of treatment was 3.8cm2/week for the honey group and 2.2cm2/week for the sugar group. After three weeks of treatment 86% of patients treated with honey had no pain during dressing changes, compared with 72% treated with sugar.
Honey appears to be more effective than sugar in reducing bacterial contamination and promoting wound healing, and slightly less painful than sugar during dressing changes and motion.
探讨蜂蜜和糖作为伤口敷料在疗效上是否存在差异。
将开放性伤口或感染伤口患者随机分为两组，分别接受蜂蜜敷料或糖敷料治疗。在治疗开始时及每周进行评估，直至伤口完全愈合，评估指标包括细菌定植情况、伤口大小、伤口无菌评分及疼痛程度。
共纳入40例患者，其中18例接受糖敷料治疗，22例接受蜂蜜敷料治疗。蜂蜜组中，治疗开始时55%的患者伤口培养呈阳性，1周时为23%；糖组分别为52%和39%。治疗前两周，蜂蜜组伤口愈合的中位速率为3.8平方厘米/周，糖组为2.2平方厘米/周。治疗三周后，接受蜂蜜治疗的患者中有86%在更换敷料时无疼痛，而接受糖治疗的患者这一比例为72%。
在减少细菌污染和促进伤口愈合方面，蜂蜜似乎比糖更有效，且在更换敷料和活动时引起的疼痛略少于糖。
