Trends Cell Biol. 1997 Oct;7(10):379. doi: 10.1016/S0962-8924(97)01134-3.
The three articles in this debate section are intended to be read as a unit. Dennis Bray's introduction sets the scene, then Baas and Brown (pages 380-384) and Hirokawa et al. (pages 384-388) argue in favour of two different models for the mechanism by which the microtubules, microfilaments and neurofilaments that make up the neuronal cytoskeleton are transported along axons. These discussions frequently involve very different interpretations of the same experiments, and finding the real answer is a complicated task. As Dennis Bray says, it's a fascinating riddle, and we hope that you will enjoy thinking about possible solutions.
这组辩论文章中的三篇旨在作为一个整体阅读。丹尼斯·布雷(Dennis Bray)的引言为这组文章奠定了基础,然后巴斯和布朗(第 380-384 页)以及广川等人(第 384-388 页)提出了两种不同的模型来解释构成神经元细胞骨架的微管、微丝和神经丝是如何沿着轴突运输的。这些讨论经常涉及对相同实验的非常不同的解释,而找到真正的答案是一项复杂的任务。正如丹尼斯·布雷(Dennis Bray)所说,这是一个引人入胜的谜题,我们希望您能喜欢思考可能的解决方案。