Schoepf U Joseph
Department of Radiology, Medical University of South Carolina, Charleston, SC 29425, USA.
Tech Vasc Interv Radiol. 2006 Dec;9(4):180-91. doi: 10.1053/j.tvir.2007.03.004.
The latest with the introduction of multidetector row computed tomography (MDCT), CT has been firmly established as the modality of choice for imaging the pulmonary arteries, particularly as the de facto first line test for imaging patients with suspected acute pulmonary embolism (PE). Before the introduction of MDCT, remaining concerns regarding CTs accuracy for diagnosis of isolated peripheral emboli had prevented the unanimous acceptance of this test as the reference standard for imaging PE. After a decade of uncertainty, there is now conclusive evidence that CT, if positive, provides reliable confirmation of the presence of PE and, more importantly, if negative effectively rules out clinically significant PE. Current endeavors to streamline and facilitate workflow for CT diagnosis of PE will further improve the acceptance, utility, and importance of this test. Examples include improvements in workflow, CT derivation of right ventricular function parameters for triage and prognostication of patients with acute PE and the comprehensive assessment of patients with acute chest pain for PE, coronary disease, aortic disease, and pulmonary disease by means of a single, contrast enhanced, ECG-synchronized CT scan. Although the diagnosis or exclusion of acute PE is the most common and important application of CT pulmonary angiography, the ease of scan acquisition and the high spatial resolution of modern CT techniques make this test ideally suited for the greatest majority of congenital and acquired, acute and chronic disorders of the pulmonary arteries.
随着多排螺旋计算机断层扫描(MDCT)的引入,CT已被牢固确立为肺动脉成像的首选方式,尤其是作为疑似急性肺栓塞(PE)患者成像的事实上的一线检查。在MDCT引入之前,对于CT诊断孤立性外周栓子的准确性仍存在担忧,这使得该检查未能被一致接受为PE成像的参考标准。经过十年的不确定性,现在有确凿证据表明,CT如果呈阳性,可提供PE存在的可靠确认,更重要的是,如果呈阴性,则可有效排除具有临床意义的PE。目前为简化和便利CT诊断PE的工作流程所做的努力将进一步提高该检查的接受度、实用性和重要性。例如,工作流程的改进、通过CT得出右心室功能参数以对急性PE患者进行分诊和预后评估,以及通过单次对比增强、心电图同步CT扫描对急性胸痛患者进行PE、冠状动脉疾病、主动脉疾病和肺部疾病的综合评估。尽管诊断或排除急性PE是CT肺动脉造影最常见和重要的应用,但扫描采集的简便性和现代CT技术的高空间分辨率使该检查非常适合大多数先天性和后天性、急性和慢性肺动脉疾病。