Bennett John, Boddy Alex, Rhodes Michael
Norfolk and Norwich University Hospital NHS Trust, Colney Lane, Norwich, UK.
Surg Laparosc Endosc Percutan Tech. 2007 Aug;17(4):245-55. doi: 10.1097/SLE.0b013e318058a117.
Although laparoscopic appendicectomy has been performed since 1983, the optimal approach for appendicectomy is still under debate. A systematic review and meta-analysis of all randomized controlled trials between 1995 and 2006 was undertaken. Studies were analyzed overall and in 2 subgroups (pre-2000 and post-2000) to examine for changes in outcomes with increased laparoscopic experience. Operation time was significantly longer for laparoscopy and hospital stay was shorter. Operating time reduced markedly for laparoscopy on subgroup analysis. The risks of postoperative ileus and wound infection are lower for laparoscopy. Perhaps paradoxically, the risk of intra-abdominal abscess development is significantly raised with laparoscopy with an odds ratio of 2.26 (P=0.0002). Laparoscopic appendicectomy is a safe and effective method of treating acute appendicitis. This meta-analysis shows improvement in the outcomes of laparoscopy with increasing laparoscopic experience but open surgery appears to still confer benefits, especially in terms of intra-abdominal abscess incidence.
尽管自1983年起就已开展腹腔镜阑尾切除术,但阑尾切除术的最佳术式仍存在争议。我们对1995年至2006年间所有随机对照试验进行了系统评价和荟萃分析。对研究进行了整体分析,并分为两个亚组(2000年前和2000年后),以检验随着腹腔镜经验增加,手术结果是否有所变化。腹腔镜手术的手术时间显著更长,但住院时间更短。亚组分析显示,腹腔镜手术的手术时间显著缩短。腹腔镜手术术后肠梗阻和伤口感染的风险更低。也许自相矛盾的是,腹腔镜手术发生腹腔内脓肿的风险显著增加,优势比为2.26(P = 0.0002)。腹腔镜阑尾切除术是治疗急性阑尾炎的一种安全有效的方法。这项荟萃分析表明,随着腹腔镜经验的增加,腹腔镜手术的结果有所改善,但开放手术似乎仍有优势,尤其是在腹腔内脓肿发生率方面。