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美国东南部HIV感染者中种族和性别与抗逆转录病毒疗法使用情况的关联

Association of race and gender with use of antiretroviral therapy among HIV-infected individuals in the Southeastern United States.

作者信息

Reif Susan, Whetten Kathryn, Thielman Nathan

机构信息

Center for Health Policy, Duke University, Durham, NC, USA.

出版信息

South Med J. 2007 Aug;100(8):775-81. doi: 10.1097/SMJ.0b013e3180f626b4.

Abstract

BACKGROUND

Women and minorities continue to account for a higher proportion of AIDS incidence and mortality than their male and white counterparts. This study examined whether race and gender were associated with antiretroviral use among HIV-infected individuals in the southeastern US.

METHODS

Multivariate regression analyses were used to identify whether race and gender predicted use of a protease inhibitor (PI) or non-nucleoside reverse transcriptase inhibitor (NNRTI) from 1996 to 2000 among individuals receiving HIV primary care.

RESULTS

Female gender and nonwhite race were significantly associated with a lower likelihood of being prescribed a PI or NNRTI at baseline. At the follow-up measure three years later, fewer individuals of minority race and female gender were prescribed a PI or NNRTI; however, these differences had declined and were no longer statistically significant.

CONCLUSIONS

Efforts are needed to improve prompt access to advances in HIV therapeutics for women and minorities and to address continued disparities in HIV care by race and gender.

摘要

背景

与男性和白人相比,女性和少数族裔在艾滋病发病率和死亡率中所占比例仍然更高。本研究调查了在美国东南部感染艾滋病毒的个体中,种族和性别是否与抗逆转录病毒药物的使用有关。

方法

采用多变量回归分析来确定在1996年至2000年期间接受艾滋病毒初级护理的个体中,种族和性别是否能预测蛋白酶抑制剂(PI)或非核苷类逆转录酶抑制剂(NNRTI)的使用情况。

结果

女性和非白人种族在基线时被开具PI或NNRTI的可能性显著较低。在三年后的随访测量中,少数族裔和女性中被开具PI或NNRTI的人数较少;然而,这些差异已经缩小,不再具有统计学意义。

结论

需要努力改善妇女和少数族裔及时获得艾滋病毒治疗进展的机会,并解决艾滋病毒护理中持续存在的种族和性别差异问题。

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