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阻塞性睡眠呼吸暂停/低通气综合征的微创单阶段多节段治疗

Minimally invasive single-stage multilevel treatment for obstructive sleep apnea/hypopnea syndrome.

作者信息

Friedman Michael, Lin Hsin-Ching, Gurpinar Berk, Joseph Ninos J

机构信息

Department of Otolaryngology and Bronchoesophagology, Rush University Medical Center, Chicago, Illinois, USA.

出版信息

Laryngoscope. 2007 Oct;117(10):1859-63. doi: 10.1097/MLG.0b013e3180f62b4d.

Abstract

OBJECTIVES

To assess subjective and objective improvement after single-stage multilevel minimally invasive treatment for obstructive sleep apnea/hypopnea syndrome (OSAHS).

STUDY DESIGN

A retrospective review of a prospective dataset of patients treated in a tertiary care referral center.

METHODS

Charts of 145 patients with mild/moderate OSAHS treated with a single-stage multilevel minimally invasive technique were reviewed to abstract pre- and posttreatment symptoms and polysomnographic data. One hundred twenty-two patients had minimum follow-up of 6 (range, 6-23) months and complete data available for analysis. All patients studied had three-level treatment that included nasal surgery, palatal stiffening by Pillar implant technique, and radiofrequency volume reduction of the tongue base. Primary outcomes included change from baseline in apnea/hypopnea index (AHI). Secondary outcomes included change in Epworth Sleepiness Scale (ESS) and bed-partner assessed snoring visual analogue scale (VAS, 0-10), pain levels, narcotic use, and complications.

RESULTS

Mean AHI decreased from 23.2 +/- 7.6 preoperatively to 14.5 +/- 10.2 postoperatively (P < .0001). Classical "cure" was achieved in 54 (47.5%) patients. Mean ESS decreased from 9.7 +/- 3.9 preoperatively to 6.9 +/- 3.3 postoperatively (P < .0001). Mean snoring VAS decreased from 9.4 +/- 0.9 preoperatively to 3.2 +/- 2.4 postoperatively (P <. 0001).

CONCLUSION

Polysomnographic respiratory parameters, ESS, and snoring VAS significantly improved in patients with mild/moderate OSAHS treated with single-stage multilevel minimally invasive surgery. Multilevel minimally invasive single-stage surgery is a valid option for selected patients with mild/moderate OSAHS with the understanding that they may require secondary treatment.

摘要

目的

评估阻塞性睡眠呼吸暂停低通气综合征(OSAHS)单阶段多级微创治疗后的主观和客观改善情况。

研究设计

对一家三级医疗转诊中心治疗的患者前瞻性数据集进行回顾性分析。

方法

回顾了145例采用单阶段多级微创技术治疗的轻/中度OSAHS患者的病历,以提取治疗前后的症状和多导睡眠图数据。122例患者的最短随访时间为6(范围6 - 23)个月,且有完整数据可供分析。所有研究患者均接受了三级治疗,包括鼻腔手术、采用Pillar植入技术进行腭部加固以及舌根射频减容术。主要结局指标包括呼吸暂停/低通气指数(AHI)相对于基线的变化。次要结局指标包括爱泼华嗜睡量表(ESS)的变化、床伴评估的打鼾视觉模拟量表(VAS,0 - 10)、疼痛程度、麻醉药物使用情况及并发症。

结果

平均AHI从术前的23.2±7.6降至术后的14.5±10.2(P <.0001)。54例(47.5%)患者实现了典型的“治愈”。平均ESS从术前的9.7±3.9降至术后的6.9±3.3(P <.0001)。平均打鼾VAS从术前的9.4±0.9降至术后的3.2±2.4(P <.0001)。

结论

采用单阶段多级微创手术治疗的轻/中度OSAHS患者,其多导睡眠图呼吸参数、ESS及打鼾VAS均有显著改善。对于部分轻/中度OSAHS患者,多级微创单阶段手术是一种有效的选择,但需了解患者可能需要二次治疗。

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