生物大分子溶液的X射线和中子散射分析。

Analysis of X-ray and neutron scattering from biomacromolecular solutions.

作者信息

Petoukhov Maxim V, Svergun Dmitri I

机构信息

EMBL, Hamburg Outstation, Germany.

出版信息

Curr Opin Struct Biol. 2007 Oct;17(5):562-71. doi: 10.1016/j.sbi.2007.06.009. Epub 2007 Aug 21.

DOI:10.1016/j.sbi.2007.06.009

PMID:17714935

Abstract

New developments in small-angle X-ray and neutron scattering studies of biological macromolecules in solution are presented. Small-angle scattering is rapidly becoming a streamline tool in structural molecular biology providing unique information about overall structure and conformational changes of native individual proteins, functional complexes, flexible macromolecules and assembly processes.

摘要

介绍了溶液中生物大分子的小角X射线和中子散射研究的新进展。小角散射正迅速成为结构分子生物学中的一种简化工具，可提供有关天然单个蛋白质、功能复合物、柔性大分子和组装过程的整体结构和构象变化的独特信息。