用于芳基氯代物铃木-宫浦反应的高效且可重复使用的负载型钯催化剂。

Highly efficient and reusable supported pd catalysts for Suzuki-Miyaura reactions of aryl chlorides.

作者信息

Schweizer Stéphane, Becht Jean-Michel, Le Drian Claude

机构信息

Université de Haute-Alsace, Ecole Nationale Supérieure de Chimie de Mulhouse Laboratoire de Chimie Organique et Bioorganique, UMR-CNRS 7015, 3 rue Alfred Werner, 68093 Mulhouse cedex, France.

出版信息

Org Lett. 2007 Sep 13;9(19):3777-80. doi: 10.1021/ol701460z. Epub 2007 Aug 23.

DOI:10.1021/ol701460z

PMID:17715929

Abstract

Syntheses of air- and moisture-stable heterogeneous (tert-butylarylphosphino)polystyrene-supported Pd catalysts and their use for versatile Suzuki-Miyaura reactions of aryl chlorides and arylboronic acids under non-anhydrous conditions are reported. The catalysts are easily recovered by filtration. They can be used many times (more than seven) without showing any loss of activity, and the amount of Pd leached is extremely low (<0.1%).

摘要

报道了空气和水分稳定的非均相（叔丁基芳基膦基）聚苯乙烯负载钯催化剂的合成及其在非无水条件下用于芳基氯与芳基硼酸的多种铃木-宫浦反应中的应用。该催化剂通过过滤易于回收。它们可以多次使用（超过七次）而不显示任何活性损失，并且钯的浸出量极低（<0.1%）。