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[神经症患者静息及体力负荷时的功能性心血管障碍]

[Functional cardiovascular disorders in patients with neuroses at rest and during physical loading].

作者信息

Juhás S, Mechír J, Kafka J, Baldovský V, Ulicianský V

机构信息

II. interná klinika Fakultnej nemocnice s poliklinikou, Kosice.

出版信息

Vnitr Lek. 1991 Sep-Oct;37(9-10):745-51.

PMID:1771806
Abstract

The authors examined using selected non-invasive cardiological examination methods 33 patients with neurosis. Four were eliminated on account of organic heart disease. From the group of 29 patients 12 had ECG changes (41%)--of those 5 (17%) had an incomplete right bundle branch block and 1 (3%) had a left anterior fascicular block; 2 (7%) had the syndrome of early repolarization and 4 (14%) had changes of the T wave. The polycardiogram did not reveal a statistically significant difference in the investigated indicators (PEPc, LVETc, WI, PVR) between the group of sick and healthy patients at rest. Ambulatory 24-hour monitoring of the ECG was done in 21 patients--in 2 (10%) it revealed a sinoatrial block, in 10 (50%) episodic sinus tachycardia, in 6 (30%) occasional supraventricular extrasystoles, in 5 (25%) rare ventricular extrasystoles. The echocardiographic examination confirmed the statistically significantly increased systolic function of the left ventricle (P less than 0.05) in all investigated parameters (%D, Vcf, MNSER, EF), as compared with healthy subjects. After a loading ECG test of 28 patients 2 (7%) had ST-T changes. Statistical comparison with the group of healthy subjects revealed in the patients with neurosis a significantly reduced value of systolic (P less than 0.005) and median blood pressure (P less than 0.01), as well as of the inner cardiac work at the peak of the submaximum load (P less than 0.05) and an increase of the diastolic blood pressure (P less than 0.05) during the 10th minute of recovery. The orthostatic test in 20 patients with neurosis revealed a significantly higher heart rate at rest and during the 30th and 60th second after rising (P less than 0.05) and a significantly lower orthostatic index (P less than 0.001) on statistical comparison with healthy subjects.

摘要

作者使用选定的非侵入性心脏检查方法对33例神经症患者进行了检查。4例因器质性心脏病被排除。在29例患者中,12例(41%)有心电图改变——其中5例(17%)有不完全性右束支传导阻滞,1例(3%)有左前分支传导阻滞;2例(7%)有早期复极综合征,4例(14%)有T波改变。静息状态下,多心电图检查未显示患病组与健康组在研究指标(PEPc、LVETc、WI、PVR)上有统计学显著差异。对21例患者进行了24小时动态心电图监测——其中2例(10%)显示有窦房阻滞,10例(50%)有阵发性窦性心动过速,6例(30%)有偶发室上性期前收缩,5例(25%)有罕见室性期前收缩。超声心动图检查证实,与健康受试者相比,所有研究参数(%D、Vcf、MNSER、EF)均显示左心室收缩功能有统计学显著增加(P<0.05)。对28例患者进行负荷心电图试验后,2例(7%)有ST-T改变。与健康受试者组进行统计学比较发现,神经症患者的收缩压(P<0.005)和平均血压(P<0.01)显著降低,次极量负荷峰值时的心内功(P<0.05)降低,恢复第10分钟时舒张压升高(P<0.05)。对20例神经症患者进行的直立试验显示,与健康受试者相比,静息时及起身第30秒和60秒时心率显著更高(P<0.05),直立指数显著更低(P<0.001)。

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