Serra Walter, De Iaco Giuseppe, Reverberi Claudio, Gherli Tiziano
Heart department, Cardiology division, Azienda Ospedaliera/Universitaria Parma, Italy.
Cardiovasc Ultrasound. 2007 Aug 24;5:26. doi: 10.1186/1476-7120-5-26.
This is a case report of a 35 young man with Klinefelter Syndrome presented breathlessness, palpitations and chest pain. It shows a rare case of a thrombus located through the PFO, in patient with pulmonary and paradoxical embolism, which takes back to exciting hypothesis on thrombus growth. A thrombus, which has grown 'in situ' or trapped through the patent foramen ovale, may be a cause of relapsing pulmonary or systemic embolism during anticoagulation therapy. To prevent recurrent paradoxical embolism, percutaneous closure of PFO is recommended, but in this case, thrombus was trapped through the PFO and the patient was referred to the surgeon. We believe that under these circumstances the clinician should be informed of the presence of PFO in critical pulmonary embolism; this case points out the key role of TEE to face a diagnostic and therapeutic scenarios.
这是一例关于一名35岁患有克兰费尔特综合征的年轻男性出现呼吸急促、心悸和胸痛的病例报告。该病例显示了一例罕见的通过卵圆孔未闭(PFO)形成血栓的情况,患者同时患有肺栓塞和反常栓塞,这引发了关于血栓形成的有趣假说。一个在原位形成或通过卵圆孔未闭被困住的血栓,可能是抗凝治疗期间复发性肺栓塞或系统性栓塞的原因。为预防复发性反常栓塞,建议行经皮卵圆孔未闭封堵术,但在本病例中,血栓通过卵圆孔未闭被困住,患者被转诊给外科医生。我们认为在这种情况下,临床医生应了解在严重肺栓塞中卵圆孔未闭的存在;该病例指出了经食管超声心动图(TEE)在面对诊断和治疗情况时的关键作用。