Chuang Sung-Kiang, Perrott David H, Susarla Srinivas M, Dodson Thomas B
Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital and Harvard School of Dental Medicine, Boston, MA 02114, USA.
J Oral Maxillofac Surg. 2007 Sep;65(9):1685-92. doi: 10.1016/j.joms.2007.04.019.
The purpose of this study was to estimate the frequency of complications after third molar (M3) surgery, with age as the primary risk factor.
This was a prospective cohort study of a sample of subjects having at least 1 M3 extracted as part of the American Association of Oral and Maxillofacial Surgeons' Age-Related Third Molar Study. The predictor variables were categorized as demographic, health status, anatomic, and pathological. The outcome variable was overall complications, including both intraoperative and postoperative complications. Appropriate univariate and bivariate statistics were computed. A multiple logistic regression model was used to evaluate the simultaneous effects of multiple covariates.
The study sample was comprised of 4,004 subjects having a total of 8,748 M3s removed. The mean age was 39.8 +/- 13.6 years, with 245 subjects (6.1%) age 25 and younger. Approximately half of the subjects were female. The overall complication rate was 19%. In bivariate analyses, age above 25 years, gender, American Society of Anesthesiologists classification, number of preoperatively identified risk factors for complication, impaction level of M3, evidence of periodontal disease, preoperative infection, and evidence of any pathology associated with M3 were associated with complications (P <or= .15). In the multiple regression model, age above 25 years was associated with an increased risk of complications (odds ratio = 1.5; P = .05).
The results of these analyses suggest that increased age (>25 years) appears to be associated with a higher complication rate for M3 extractions.
本研究旨在以年龄作为主要风险因素,评估第三磨牙(M3)手术后并发症的发生率。
这是一项前瞻性队列研究,研究对象为美国口腔颌面外科医师协会年龄相关第三磨牙研究中至少拔除一颗M3的受试者样本。预测变量分为人口统计学、健康状况、解剖学和病理学变量。结果变量为总体并发症,包括术中及术后并发症。计算了适当的单变量和双变量统计量。使用多元逻辑回归模型评估多个协变量的同时效应。
研究样本包括4004名受试者,共拔除8748颗M3。平均年龄为39.8±13.6岁,其中245名受试者(6.1%)年龄在25岁及以下。约一半受试者为女性。总体并发症发生率为19%。在双变量分析中,25岁以上年龄、性别、美国麻醉医师协会分级、术前确定的并发症危险因素数量、M3的阻生水平、牙周疾病证据、术前感染以及与M3相关的任何病理学证据均与并发症相关(P≤0.15)。在多元回归模型中,25岁以上年龄与并发症风险增加相关(比值比=1.5;P=0.05)。
这些分析结果表明,年龄增加(>25岁)似乎与M3拔除术后较高的并发症发生率相关。