采用线扫描扩散加权成像评估垂体大腺瘤的表观扩散系数。
Apparent diffusion coefficient of pituitary macroadenoma evaluated with line-scan diffusion-weighted imaging.
作者信息
Suzuki C, Maeda M, Hori K, Kozuka Y, Sakuma H, Taki W, Takeda K
机构信息
Department of Radiology, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan.
出版信息
J Neuroradiol. 2007 Oct;34(4):228-35. doi: 10.1016/j.neurad.2007.06.007. Epub 2007 Aug 24.
OBJECTIVE
The goal of this study was to evaluate the consistency of pituitary macroadenoma using apparent diffusion coefficient (ADC) with line-scan diffusion-weighted imaging (LSDWI).
METHODS
Patients with pituitary macroadenoma (n=19) were studied prospectively. The LSDWI was performed using a maximum b factor of 1000 s/mm2. The consistency of macroadenoma was rated as soft, intermediate or hard at transsphenoidal surgery. The ADC values of tumors were compared with the tumor-consistency ratings.
RESULTS
A soft consistency was found at surgery in 13 patients (mean ADC: 0.84+/-0.1x10(-3) mm2/s); an intermediate consistency was observed in six patients (mean ADC: 0.81+/-0.16x10(-3) mm2/s). No tumors of hard consistency were found. There was no significant difference in ADC values between tumors of soft consistency compared with tumors of intermediate consistency (P=0.37).
CONCLUSIONS
A relationship between tumor consistency and the ADCs of soft and intermediate macroadenomas was not shown in this study using LSDWI.
目的
本研究的目的是使用线扫描扩散加权成像（LSDWI）评估垂体大腺瘤表观扩散系数（ADC）的一致性。
方法
对19例垂体大腺瘤患者进行前瞻性研究。使用最大b值为1000 s/mm2进行LSDWI。在经蝶窦手术中，将大腺瘤的一致性分为软、中等或硬。比较肿瘤的ADC值与肿瘤一致性评级。
结果
13例患者在手术中发现为软一致性（平均ADC：0.84±0.1×10(-3) mm2/s）；6例患者观察到中等一致性（平均ADC：0.81±0.16×10(-3) mm2/s）。未发现硬一致性肿瘤。软一致性肿瘤与中等一致性肿瘤的ADC值之间无显著差异（P = 0.37）。
结论
本研究使用LSDWI未显示软和中等大腺瘤的肿瘤一致性与ADC之间的关系。
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