Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawaharacho, Sakyoku, Kyoto, 606-8507, Japan.
Department of Advanced Imaging in Medical Magnetic Resonance, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawaharacho, Sakyoku, Kyoto, 606-8507, Japan.
Eur Radiol Exp. 2024 Mar 7;8(1):28. doi: 10.1186/s41747-024-00430-8.
To evaluate the clinical usefulness of thin-slice echo-planar imaging (EPI)-based diffusion-weighted imaging (DWI) with an on-console distortion correction technique, termed reverse encoding distortion correction DWI (RDC-DWI), in patients with non-functioning pituitary neuroendocrine tumor (PitNET)/pituitary adenoma.
Patients with non-functioning PitNET/pituitary adenoma who underwent 3-T RDC-DWI between December 2021 and September 2022 were retrospectively enrolled. Image quality was compared among RDC-DWI, DWI with correction for distortion induced by B inhomogeneity alone (B-corrected-DWI), and original EPI-based DWI with anterior-posterior phase-encoding direction (AP-DWI). Susceptibility artifact, anatomical visualization of cranial nerves, overall tumor visualization, and visualization of cavernous sinus invasion were assessed qualitatively. Quantitative assessment of geometric distortion was performed by evaluation of anterior and posterior displacement between each DWI and the corresponding three-dimensional T2-weighted imaging. Signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and apparent diffusion coefficient values were measured.
Sixty-four patients (age 70.8 ± 9.9 years [mean ± standard deviation]; 33 females) with non-functioning PitNET/pituitary adenoma were evaluated. In terms of susceptibility artifacts in the frontal and temporal lobes, visualization of left trigeminal nerve, overall tumor visualization, and anterior displacement, RDC-DWI performed the best and B-corrected-DWI performed better than AP-DWI. The right oculomotor and right trigeminal nerves were better visualized by RDC-DWI than by B-corrected-DWI and AP-DWI. Visualization of cavernous sinus invasion and posterior displacement were better by RDC-DWI and B-corrected-DWI than by AP-DWI. SNR and CNR were the highest for RDC-DWI.
RDC-DWI achieved excellent image quality regarding susceptibility artifact, geometric distortion, and tumor visualization in patients with non-functioning PitNET/pituitary adenoma.
RDC-DWI facilitates excellent visualization of the pituitary region and surrounding normal structures, and its on-console distortion correction technique is convenient. RDC-DWI can clearly depict cavernous sinus invasion of PitNET/pituitary adenoma even without contrast medium.
• RDC-DWI is an EPI-based DWI technique with a novel on-console distortion correction technique. • RDC-DWI corrects distortion due to B field inhomogeneity and eddy current. • We evaluated the usefulness of thin-slice RDC-DWI in non-functioning PitNET/pituitary adenoma. • RDC-DWI exhibited excellent visualization in the pituitary region and surrounding structures. • In addition, the on-console distortion correction of RDC-DWI is clinically convenient.
为了评估基于薄切片回波平面成像（EPI）的扩散加权成像（DWI）联合控制台反转编码失真校正技术（RDC-DWI）在无功能垂体神经内分泌肿瘤（PitNET）/垂体腺瘤患者中的临床应用价值。
回顾性纳入 2021 年 12 月至 2022 年 9 月间在 3T 场强下接受 RDC-DWI 的无功能 PitNET/垂体腺瘤患者。对比 RDC-DWI、仅校正 B 不均匀性引起的失真的 DWI（B 校正-DWI）和原始基于 EPI 的前后相位编码方向 DWI（AP-DWI）的图像质量。定性评估磁敏感伪影、颅神经解剖显示、肿瘤整体显示和海绵窦侵犯的显示。通过评估每个 DWI 与相应的三维 T2 加权成像之间的前后位移，对几何失真进行定量评估。测量信噪比（SNR）、对比噪声比（CNR）和表观扩散系数值。
共评估了 64 例无功能 PitNET/垂体腺瘤患者（年龄 70.8±9.9 岁[均值±标准差]；33 例女性）。在额叶和颞叶的磁敏感伪影、左侧三叉神经的显示、肿瘤整体显示和前向位移方面，RDC-DWI 表现最好，B 校正-DWI 优于 AP-DWI。RDC-DWI 比 B 校正-DWI 和 AP-DWI 更能显示右侧动眼神经和右侧三叉神经。RDC-DWI 和 B 校正-DWI 比 AP-DWI 更能显示海绵窦侵犯和后向位移。RDC-DWI 的 SNR 和 CNR 最高。
RDC-DWI 可显著改善无功能 PitNET/垂体腺瘤患者的磁敏感伪影、几何失真和肿瘤显示质量。
RDC-DWI 有助于清晰显示垂体区域及其周围正常结构，其内置的失真校正技术方便实用。即使不使用造影剂，RDC-DWI 也能清晰显示垂体腺瘤的海绵窦侵犯。
RDC-DWI 是一种基于 EPI 的 DWI 技术，具有新颖的内置失真校正技术。
RDC-DWI 校正 B 场不均匀性和涡流引起的失真。
我们评估了薄切片 RDC-DWI 在无功能 PitNET/垂体腺瘤中的应用价值。
RDC-DWI 在垂体区域和周围结构的显示方面表现出色。
此外，RDC-DWI 的内置失真校正在临床应用中非常方便。
