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卡塔尔青年缺血性卒中的危险因素。

Risk factors of young ischemic stroke in Qatar.

作者信息

Khan Fahmi Yousef

机构信息

Department of Medicine, Hamad General Hospital, P.O. Box 3050, Doha, Qatar.

出版信息

Clin Neurol Neurosurg. 2007 Nov;109(9):770-3. doi: 10.1016/j.clineuro.2007.07.006. Epub 2007 Aug 27.

Abstract

OBJECTIVES

There is limited information about risk factors of young ischemic stroke in Qatar. The aim of this study was to describe the risk factors and subtypes of young ischemic stroke among Qatari and non-Qatari residents.

PATIENTS AND METHODS

Hospital based prospective observational study involving all young adults (15-45 years of age) admitted to Hamad General Hospital with first-ever ischemic stroke from September 2004 to September 2005. A stroke was defined according to WHO criteria.

RESULTS

Stroke was confirmed in 40 (32 males and 8 females). Their ages ranged from 17 to 44 years (mean 37.1+/-13.27). Thirty (75%) of the patients were non-Qatari. The most common risk factors were hypertension 16 (40%), diabetes mellitus 13 (32.5%), hypercholesterolemia 11 (27.5%), smoking 11 (27.5%), and alcohol intake 9 (22.5%). Regarding stroke subtypes, lacunar stroke syndrome (LACS) was diagnosed in 17 (42.5%), total anterior circulation stroke syndrome (TACS) in 16 (40%), partial anterior circulation stroke syndrome (PACS) in 5 (12.5%) and posterior circulation stroke syndrome (POCS) in 2 (5%). Partial anterior circulation stroke syndrome (PACS) was observed with a higher frequency in Qatari patients compared with non-Qataris (p=0.009), whereas total anterior circulation stroke syndrome (TACS) was observed more in non-Qatari than in Qatari patients (p=0.03). Average hospital stay was 18 days. In-hospital mortality was 2.5%.

CONCLUSION

The risk factors of ischemic stroke in young adults are numerous. The most common were hypertension, diabetes mellitus, hypercholesterolemia, smoking and alcohol intake. Only one Indonesian male patient with POCS died in the hospital.

摘要

目的

关于卡塔尔青年缺血性卒中危险因素的信息有限。本研究旨在描述卡塔尔和非卡塔尔居民中年轻缺血性卒中的危险因素及亚型。

患者与方法

基于医院的前瞻性观察性研究,纳入2004年9月至2005年9月期间因首次缺血性卒中入住哈马德总医院的所有青年成年人(15 - 45岁)。卒中根据世界卫生组织标准定义。

结果

共确诊40例卒中患者(32例男性,8例女性)。年龄范围为17至44岁(平均37.1±13.27岁)。30例(75%)患者为非卡塔尔人。最常见的危险因素为高血压16例(40%)、糖尿病13例(32.5%)、高胆固醇血症11例(27.5%)、吸烟11例(27.5%)和饮酒9例(22.5%)。关于卒中亚型,腔隙性卒中综合征(LACS)诊断为17例(42.5%),完全前循环卒中综合征(TACS)16例(40%),部分前循环卒中综合征(PACS)5例(12.5%),后循环卒中综合征(POCS)2例(5%)。与非卡塔尔患者相比,卡塔尔患者中部分前循环卒中综合征(PACS)的发生率更高(p = 0.009),而完全前循环卒中综合征(TACS)在非卡塔尔患者中的发生率高于卡塔尔患者(p = 0.03)。平均住院时间为18天。院内死亡率为2.5%。

结论

青年成年人缺血性卒中的危险因素众多。最常见的是高血压、糖尿病、高胆固醇血症、吸烟和饮酒。仅1例患有POCS的印度尼西亚男性患者在医院死亡。

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