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卡塔尔中风的现状:包括来自BRAINS研究的数据。

Current status of stroke in Qatar: Including data from the BRAINS study.

作者信息

Jallow Ebrima, Al Hail Hassan, Han Thang S, Sharma Sapna, Deleu Dirk, Ali Musab, Al Hussein Hassan, Abuzaid Hassan O, Sharif Khalid, Khan Fahmi Y, Sharma Pankaj

机构信息

Institute of Cardiovascular Research, Royal Holloway University of London , London, UK.

Hamad Medical Corporation, Doha, Qatar.

出版信息

JRSM Cardiovasc Dis. 2019 Aug 18;8:2048004019869160. doi: 10.1177/2048004019869160. eCollection 2019 Jan-Dec.

Abstract

BACKGROUND

Qatar is located on the north-eastern coast of the Arabian Peninsula. Qatari natives account for less than 15% of the population while the largest migrant group comprising 60% derives from South Asia. Despite projections that stroke burden in Qatar will increase with population ageing, epidemiological studies focusing on stroke in Qatar are relatively scarce.

METHOD

We reviewed the available epidemiological publications relating to Qatar. In addition, we have added to this knowledge by incorporating Qatari data from the on-going Bio-Repository of DNA in Stroke, an independent multinational database of stroke patients.

RESULTS

Qatar has low reported incidence and mortality rates of 58 and 9.17 per 100,000 per year, respectively, which may be explained by its middle-aged migrant worker majority population. Correspondingly, South Asian migrants in Qatar suffered younger strokes than Qatari natives (48.7 vs 63.4 years, P < 0.001). Among the most common risk factors identified in stroke patients were hypertension (77.9%), diabetes (43.8%) and hypercholesterolemia (28.5%). Ischaemic stroke was the most frequent subtype amongst migrant South Asians (71.1%). The majority of stroke cases had computed tomography and/or magnetic resonance imaging scans, but only 11.1% of ischaemic strokes were thrombolysed. Qataris on one-year follow up were more often found to have died (6.5% vs 0.3%) and had further stroke/transient ischaemic attack events (17.4% vs 6.4%, P = 0.009) compared to South Asians.

CONCLUSION

The burden of stroke is increasing in Qatar, and considerable disparities are observed between the native and migrant populations which likely will require different approaches to management by its healthcare system.

摘要

背景

卡塔尔位于阿拉伯半岛的东北海岸。卡塔尔本地人占人口比例不到15%,而最大的移民群体占60%,来自南亚。尽管预计随着卡塔尔人口老龄化,中风负担将会增加,但针对卡塔尔中风情况的流行病学研究相对较少。

方法

我们查阅了与卡塔尔相关的现有流行病学出版物。此外,我们通过纳入来自正在进行的中风DNA生物样本库(一个独立的中风患者跨国数据库)的卡塔尔数据,补充了这方面的知识。

结果

据报告,卡塔尔的发病率和死亡率较低,分别为每年每10万人58例和9.17例,这可能是由于其以中年移民工人为主的人口结构所致。相应地,卡塔尔的南亚移民中风发病年龄比卡塔尔本地人年轻(48.7岁对63.4岁,P<0.001)。在中风患者中确定的最常见风险因素包括高血压(77.9%)、糖尿病(43.8%)和高胆固醇血症(28.5%)。缺血性中风是南亚移民中最常见的亚型(71.1%)。大多数中风病例进行了计算机断层扫描和/或磁共振成像扫描,但只有11.1%的缺血性中风接受了溶栓治疗。与南亚人相比,对卡塔尔人进行一年随访时发现,死亡的比例更高(6.5%对0.3%),发生进一步中风/短暂性脑缺血发作事件的比例也更高(17.4%对6.4%,P=0.009)。

结论

卡塔尔的中风负担正在增加,本地人和移民人口之间存在显著差异,这可能需要其医疗系统采取不同的管理方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f7e/6700866/e51325fb8712/10.1177_2048004019869160-fig1.jpg

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