Ghazawy Samer, Reddy Aravind R, Kipioti Athina, McShane Phil, Arora Seema, Bradbury John A
Department of Ophthalmology, St James' University Hospital, Leeds, UK.
J AAPOS. 2007 Dec;11(6):601-5. doi: 10.1016/j.jaapos.2007.06.011. Epub 2007 Aug 27.
Inferior oblique overaction can be either secondary (as a sequela of ipsilateral superior oblique palsy) or primary (commonly associated with horizontal strabismus). Superior oblique underaction often coexists with both primary and secondary inferior oblique overaction. This retrospective case series compares the efficacy of inferior oblique myectomy versus anterior transposition in improving inferior oblique overaction and superior oblique underaction in eyes with either primary or secondary inferior oblique overaction.
One hundred twenty eyes of 81 patients were included in this retrospective case series, of which 20 had anterior transposition of the inferior oblique and 100 eyes underwent myectomy. Inferior oblique myectomy was compared with inferior oblique anterior transposition in improving inferior oblique overaction and superior oblique underaction in each diagnostic subgroup. Postoperative outcome was qualitatively and quantitatively assessed. Fisher's exact test was used to compare the outcomes. The quantitative improvement of function in terms of inferior oblique overaction and superior oblique underaction was analyzed by regression analysis.
When postoperative inferior oblique overaction was considered, there was no statistically significant difference between myectomy and anterior transposition in both primary and secondary inferior oblique overaction. Myectomy was superior to anterior transposition in improving superior oblique underaction in both primary inferior oblique overaction (OR = 0.14; 95% CI, 0.015-1.45; p = 0.056) and secondary inferior oblique overaction (OR = 0; 95% CI, 0-0.027; p < 0.001). The quantitative improvement of function showed a significant difference between procedures for superior oblique underaction (t-test; p = 0.005; 95% CI, 0.25-1.3) but not inferior oblique overaction (t-test; p = 0.8; 95% CI, -0.67-0.54).
This study demonstrates both inferior oblique myectomy and inferior oblique anterior transposition to be effective in correcting primary and secondary inferior oblique overaction. Myectomy is more effective in improving superior oblique underaction associated with both primary and secondary inferior oblique overaction. On this basis, we feel that inferior oblique myectomy has some advantage over anterior transposition in treating combined inferior oblique overaction and superior oblique underaction and can be considered the procedure of choice.
下斜肌亢进可继发(作为同侧上斜肌麻痹的后遗症)或原发(通常与水平斜视相关)。上斜肌功能不足常与原发和继发的下斜肌亢进并存。本回顾性病例系列比较了下斜肌切除术与下斜肌前徙术在改善原发或继发下斜肌亢进及上斜肌功能不足方面的疗效。
本回顾性病例系列纳入了81例患者的120只眼,其中20只眼行下斜肌前徙术,100只眼行下斜肌切除术。在每个诊断亚组中,比较下斜肌切除术与下斜肌前徙术在改善下斜肌亢进及上斜肌功能不足方面的效果。对术后结果进行定性和定量评估。采用Fisher精确检验比较结果。通过回归分析分析下斜肌亢进和上斜肌功能不足方面功能的定量改善情况。
在考虑术后下斜肌亢进时,下斜肌切除术与下斜肌前徙术在原发和继发下斜肌亢进方面均无统计学显著差异。在下斜肌切除术在改善原发下斜肌亢进(OR = 0.14;95% CI,0.015 - 1.45;p = 0.056)和继发下斜肌亢进(OR = 0;95% CI,0 - 0.027;p < 0.001)的上斜肌功能不足方面均优于下斜肌前徙术。功能的定量改善显示,在上斜肌功能不足方面手术之间存在显著差异(t检验;p = 0.005;95% CI,0.25 - 1.3),但在下斜肌亢进方面无显著差异(t检验;p = 0.8;95% CI,-0.67 - 0.54)。
本研究表明下斜肌切除术和下斜肌前徙术在纠正原发和继发下斜肌亢进方面均有效。下斜肌切除术在改善与原发和继发下斜肌亢进相关的上斜肌功能不足方面更有效。在此基础上,我们认为下斜肌切除术在治疗合并的下斜肌亢进和上斜肌功能不足方面比下斜肌前徙术具有一定优势,可被视为首选手术方式。