Bekendam Peter D, Narváez Julio, Agarwal Madhu
Department of Ophthalmology, Loma Linda University Medical Center, Loma Linda, CA, USA.
Cornea. 2007 Sep;26(8):1002-3. doi: 10.1097/ICO.0b013e3180cfe626.
To report a case of corneal melting associated with the use of the topical nonsteroidal anti-inflammatory agent Nepafenac.
Case report and literature review.
A 62-year-old woman with a complicated ocular history developed corneal melting associated with the use of Nepafenac. On discontinuation of Nepafenac, the melt rapidly resolved.
Topical nonsteroidal anti-inflammatory agents have been associated with corneal ulceration and stromal melts. This is, to our knowledge, the first reported case involving the new agent, Nepafenac.