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Case of corneal melting associated with the use of topical nepafenac.

作者信息

Bekendam Peter D, Narváez Julio, Agarwal Madhu

机构信息

Department of Ophthalmology, Loma Linda University Medical Center, Loma Linda, CA, USA.

出版信息

Cornea. 2007 Sep;26(8):1002-3. doi: 10.1097/ICO.0b013e3180cfe626.

Abstract

PURPOSE

To report a case of corneal melting associated with the use of the topical nonsteroidal anti-inflammatory agent Nepafenac.

METHODS

Case report and literature review.

RESULTS

A 62-year-old woman with a complicated ocular history developed corneal melting associated with the use of Nepafenac. On discontinuation of Nepafenac, the melt rapidly resolved.

CONCLUSIONS

Topical nonsteroidal anti-inflammatory agents have been associated with corneal ulceration and stromal melts. This is, to our knowledge, the first reported case involving the new agent, Nepafenac.

摘要

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