白内障手术和非甾体抗炎药。
Cataract surgery and nonsteroidal antiinflammatory drugs.
出版信息
J Cataract Refract Surg. 2016 Sep;42(9):1368-1379. doi: 10.1016/j.jcrs.2016.06.006.
Abstract
UNLABELLED
Nonsteroidal antiinflammatory drugs (NSAIDs) have become an important adjunctive tool for surgeons performing routine and complicated cataract surgery. These medications have been found to reduce pain, prevent intraoperative miosis, modulate postoperative inflammation, and reduce the incidence of cystoid macular edema (CME). Whether used alone, synergistically with steroids, or for specific high-risk eyes prone to the development of CME, the effectiveness of these medications is compelling. This review describes the potential preoperative, intraoperative, and postoperative uses of NSAIDs, including the potency, indications and treatment paradigms and adverse effects and contraindications. A thorough understanding of these issues will help surgeons maximize the therapeutic benefits of these agents and improve surgical outcomes.
FINANCIAL DISCLOSURE
Proprietary or commercial disclosures are listed after the references.
摘要
摘要：非甾体类抗炎药（NSAIDs）已成为常规和复杂白内障手术医生的重要辅助工具。这些药物已被发现可减轻疼痛、预防术中瞳孔缩小、调节术后炎症并降低囊样黄斑水肿（CME）的发生率。无论是单独使用，还是与类固醇联合使用，或是用于特定易发生 CME 的高危眼，这些药物的疗效都令人信服。本综述描述了 NSAIDs 的潜在术前、术中和术后用途，包括其效价、适应证和治疗方案以及不良反应和禁忌证。深入了解这些问题将有助于外科医生最大限度地发挥这些药物的治疗益处并改善手术结果。
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