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良性阵发性位置性眩晕患者热量反应及预后的监测

Monitoring of caloric response and outcome in patients with benign paroxysmal positional vertigo.

作者信息

Molina Maria I, López-Escámez Jose A, Zapata Cristobal, Vergara Laura

机构信息

Otology & Neurotology Group CTS495, Department of Surgery, Hospital de Poniente de Almería, El Ejido, Almería, Spain.

出版信息

Otol Neurotol. 2007 Sep;28(6):798-800. doi: 10.1097/MAO.0b013e318067e322.

Abstract

OBJECTIVE

To analyze the time course of caloric response in patients with Benign Paroxysmal Positional Vertigo (BPPV).

PATIENTS

Seventy-four individuals with diagnosis of BPPV during Dix-Hallpike (DH) test.

STUDY DESIGN

A prospective, longitudinal study.

SETTING

A tertiary referral center.

INTERVENTION

Patients were treated by particle repositioning maneuvers according to the affected canal, and the effectiveness was evaluated at 180 and 360 days. Bithermal caloric response was obtained by using 44 and 30 degrees C water irrigations at diagnosis, 6 months, and 1 year after.

MAIN OUTCOME MEASURE

Canal paresis (CP) and response to DH after treatment.

RESULTS

The effectiveness of the treatment for BPPV (absence of vertigo and positional nystagmus during DH) was 65.2% (45 of 69) after 1 year of follow-up. Twenty-five percent of (16 of 64) individuals with BPPV presented CP at diagnosis, 27% (12 of 44) at 6 months, and 16% (9 of 56) 1 year after. One year after, seven individuals with CP showed a normal caloric response, another seven demonstrated persistent CP, and one case developed a bilateral CP. The effectiveness of particle repositioning maneuvers was not significantly different between subjects with or without CP after 1 year of follow-up (odds ratio, 1.31 [95% confidence intervals, 0.35-4.89], p = 0.88).

CONCLUSION

Canal paresis is not associated with a lower outcome to repositioning.

摘要

目的

分析良性阵发性位置性眩晕(BPPV)患者的冷热反应时间进程。

患者

74例在Dix-Hallpike(DH)试验中诊断为BPPV的个体。

研究设计

一项前瞻性纵向研究。

研究地点

一家三级转诊中心。

干预措施

根据患侧半规管对患者进行颗粒复位手法治疗,并在180天和360天时评估疗效。在诊断时、6个月和1年后,通过用44℃和30℃水冲洗获得双侧冷热反应。

主要观察指标

半规管轻瘫(CP)及治疗后对DH试验的反应。

结果

随访1年后,BPPV治疗的有效率(DH试验期间无眩晕和位置性眼球震颤)为65.2%(69例中的45例)。25%(64例中的16例)的BPPV患者在诊断时出现CP,6个月时为27%(44例中的12例),1年后为16%(56例中的9例)。1年后,7例CP患者冷热反应恢复正常,另外7例仍持续存在CP,1例发展为双侧CP。随访1年后,有或无CP的受试者之间颗粒复位手法的疗效无显著差异(优势比,1.31[95%置信区间,0.35 - 4.89],p = 0.88)。

结论

半规管轻瘫与复位治疗效果降低无关。

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