[结核病：268例儿科患者的流行病学与临床研究]

[Tuberculosis: epidemiologic and clinical study of 268 pediatric patients].

作者信息

Domínguez Fenolle P, Cenarro Guerrero T, Rivas Chamorro A, Rituerto Gómez B, Franco López Y, de Juan Martín F

机构信息

Servicio de Pediatría, Hospital Infantil Miguel Servet, Zaragoza.

出版信息

An Esp Pediatr. 1991 Jul;35(1):26-30.

PMID:1772168

Abstract

TBC begins to be a big health problem at this moment. It was achieved a retrospective study with 238 cases in infant age, entered at Infections Section of Children's Hospital "Miguel Servet" of Zaragoza, during 18 years (1972-1989) studying epidemiologic and clinic factors. We divided in two groups: the first, latent disease (TBC turn) and the second, patent disease. The found incidence was 0.17%. The most affected group were among 0-5 years old (39.075%) of whom 53.76% were male. It was a little prevalence during winter and spring months. The middle-drop social class were the most affected. The epidemiologic ambient was positive in 31.4%. Only were vaccinated 33.6% of children. We observed more clinic forms among nonvaccinated. The lung-form (59.6%) and pleurisy (14.2%) were the most frequent found forms. The less frequent form was miliary TBC (0.96%). The parenquimatosa infiltration was the most frequent found form (42.5%).

摘要

目前，结核病开始成为一个重大的健康问题。我们对萨拉戈萨“米格尔·塞尔维特”儿童医院感染科在18年（1972 - 1989年）期间收治的238例婴幼儿病例进行了一项回顾性研究，以探讨流行病学和临床因素。我们将其分为两组：第一组为潜伏性疾病（结核菌素试验阳性），第二组为显性疾病。发现的发病率为0.17%。受影响最严重的群体是0至5岁的儿童（占39.075%），其中53.76%为男性。在冬季和春季发病率略高。社会中层阶级受影响最大。31.4%的流行病学环境呈阳性。只有33.6%的儿童接种了疫苗。我们在未接种疫苗的儿童中观察到更多的临床症状。肺部症状（59.6%）和胸膜炎（14.2%）是最常见的症状。最不常见的症状是粟粒性结核病（0.96%）。实质性浸润是最常见的症状（42.5%）。