Yeh Shing-Shing, Schuster Michael W
Northport VAMC, Geriatric division, Northport, NY 11768, USA.
Int J Nanomedicine. 2006;1(4):411-6. doi: 10.2147/nano.2006.1.4.411.
The aim is to review major clinical trials that have used megestrol acetate (MA) in the treatment of cachexia across several disease states. A review of general usage and potential side-effects are discussed. A theory that the newly approved nanocrystal formation of MA can better deliver this potent medication for treatment will also be reviewed.
目的是回顾在多种疾病状态下使用醋酸甲地孕酮(MA)治疗恶病质的主要临床试验。讨论其一般用法和潜在副作用。还将回顾一种理论,即新批准的MA纳米晶形成可以更好地递送这种强效药物用于治疗。