Balancing mucosal immunity: caught between CYLD and Charybdis.
作者信息
Kolls Jay K
机构信息
Children's Hospital of Pittsburgh, Suite 3765, 3705 Fifth Avenue, Pittsburgh, PA 15213, USA.
出版信息
Immunity. 2007 Aug;27(2):187-9. doi: 10.1016/j.immuni.2007.08.004.
PMID:17723213
Abstract
The molecular mechanism of acute lung injury caused by Streptococcus pneumoniae is unclear. In this issue of Immunity, Lim et al. (2007) demonstrate that CYLD, a deubiquinating enzyme, represses the expression of plasminogen activator inhibitor-1, which is critical in preventing tissue damage.
摘要
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