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血液透析和腹膜透析患者贫血的管理(第8章)

Management of anaemia in haemodialysis and peritoneal dialysis patients (chapter 8).

作者信息

Richardson Donald, Hodsman Alex, van Schalkwyk Dirk, Tomson Charlie, Warwick Graham

机构信息

York NHS Hospitals Trust, York UK.

出版信息

Nephrol Dial Transplant. 2007 Aug;22 Suppl 7:vii78-104. doi: 10.1093/ndt/gfm332.

Abstract

Forty-one percent of UK patients commence RRT with an Hb < 10.0 g/dl. The mean Hb at commencement of RRT is 10.3 g/dl. Eighty-five percent of patients on dialysis in the UK have an Hb > or = 10.0 g/dl by 6 months after commencement of RRT. The median Hb on haemodialysis in the UK is 11.8 g/dl with an IQR of 10.7-12.8 g/dl. Eighty-six percent of haemodialysis patients in the UK have a Hb > or = 10.0 g/dl. The median Hb on peritoneal dialysis in the UK is 12.0 g/dl with an IQR of 11.0-12.9 g/dl. Ninety percent of peritoneal dialysis patients in the UK have an Hb > or = 10.0 g/dl. In the UK, 49% of patients on PD and 48% of patients on haemodialysis have an Hb between 10.5-12.5 g/dl. The median ferritin in UK haemodialysis patients is 413 microg/l (IQR 262-623), 95% of UK haemodialysis patients have a ferritin > or =100 microg/l. The median ferritin in UK PD patients is 256 microg/l (IQR 147-421), 86% of UK peritoneal dialysis patients have a ferritin > or = 100 microg/l. A higher proportion of HD patients than PD patients receive ESA therapy (88% vs 76%). The ESA dose is higher for HD than PD patients (9204 vs 6080 IU/week).

摘要

41%的英国患者开始接受肾脏替代治疗(RRT)时血红蛋白(Hb)<10.0 g/dl。开始RRT时的平均Hb为10.3 g/dl。在英国,85%的透析患者在开始RRT后6个月时Hb≥10.0 g/dl。英国血液透析患者的Hb中位数为11.8 g/dl,四分位间距为10.7 - 12.8 g/dl。英国86%的血液透析患者Hb≥10.0 g/dl。英国腹膜透析患者的Hb中位数为12.0 g/dl,四分位间距为11.0 - 12.9 g/dl。英国90%的腹膜透析患者Hb≥10.0 g/dl。在英国,49%的腹膜透析患者和48%的血液透析患者Hb在10.5 - 12.5 g/dl之间。英国血液透析患者的铁蛋白中位数为413μg/l(四分位间距262 - 623),95%的英国血液透析患者铁蛋白≥100μg/l。英国腹膜透析患者的铁蛋白中位数为256μg/l(四分位间距147 - 421),86%的英国腹膜透析患者铁蛋白≥100μg/l。接受促红细胞生成素(ESA)治疗的血液透析患者比例高于腹膜透析患者(88%对76%)。血液透析患者的ESA剂量高于腹膜透析患者(9204对6080 IU/周)。

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