Richardson Donald, Hodsman Alex, van Schalkwyk Dirk, Tomson Charlie, Warwick Graham
York NHS Hospitals Trust, York UK.
Nephrol Dial Transplant. 2007 Aug;22 Suppl 7:vii78-104. doi: 10.1093/ndt/gfm332.
Forty-one percent of UK patients commence RRT with an Hb < 10.0 g/dl. The mean Hb at commencement of RRT is 10.3 g/dl. Eighty-five percent of patients on dialysis in the UK have an Hb > or = 10.0 g/dl by 6 months after commencement of RRT. The median Hb on haemodialysis in the UK is 11.8 g/dl with an IQR of 10.7-12.8 g/dl. Eighty-six percent of haemodialysis patients in the UK have a Hb > or = 10.0 g/dl. The median Hb on peritoneal dialysis in the UK is 12.0 g/dl with an IQR of 11.0-12.9 g/dl. Ninety percent of peritoneal dialysis patients in the UK have an Hb > or = 10.0 g/dl. In the UK, 49% of patients on PD and 48% of patients on haemodialysis have an Hb between 10.5-12.5 g/dl. The median ferritin in UK haemodialysis patients is 413 microg/l (IQR 262-623), 95% of UK haemodialysis patients have a ferritin > or =100 microg/l. The median ferritin in UK PD patients is 256 microg/l (IQR 147-421), 86% of UK peritoneal dialysis patients have a ferritin > or = 100 microg/l. A higher proportion of HD patients than PD patients receive ESA therapy (88% vs 76%). The ESA dose is higher for HD than PD patients (9204 vs 6080 IU/week).
41%的英国患者开始接受肾脏替代治疗(RRT)时血红蛋白(Hb)<10.0 g/dl。开始RRT时的平均Hb为10.3 g/dl。在英国,85%的透析患者在开始RRT后6个月时Hb≥10.0 g/dl。英国血液透析患者的Hb中位数为11.8 g/dl,四分位间距为10.7 - 12.8 g/dl。英国86%的血液透析患者Hb≥10.0 g/dl。英国腹膜透析患者的Hb中位数为12.0 g/dl,四分位间距为11.0 - 12.9 g/dl。英国90%的腹膜透析患者Hb≥10.0 g/dl。在英国,49%的腹膜透析患者和48%的血液透析患者Hb在10.5 - 12.5 g/dl之间。英国血液透析患者的铁蛋白中位数为413μg/l(四分位间距262 - 623),95%的英国血液透析患者铁蛋白≥100μg/l。英国腹膜透析患者的铁蛋白中位数为256μg/l(四分位间距147 - 421),86%的英国腹膜透析患者铁蛋白≥100μg/l。接受促红细胞生成素(ESA)治疗的血液透析患者比例高于腹膜透析患者(88%对76%)。血液透析患者的ESA剂量高于腹膜透析患者(9204对6080 IU/周)。