Müssig K, Maser-Gluth C, Hartmann M, Wehrmann M, Horger M, Kanz L, Häring H-U, Wudy S A
Abt für Endokrinologie, Diabetes, Angiologie, Nephrologie und Klinische Chemie, Medizinische Universitätsklinik Tübingen, Otfried-Müller-Strasse 10, 72076, Tübingen, Germany.
Internist (Berl). 2007 Oct;48(10):1145-50. doi: 10.1007/s00108-007-1930-x.
Ectopic ACTH syndrome is a rare differential diagnosis of hypokalemic hypertension. Patients with ectopic ACTH syndrome due to small cell lung cancer have a poor prognosis. We report on a 68-year-old female patient who presented with dyspnea and hypokalemic hypertension. Endocrine testing was consistent with ectopic ACTH syndrome due to small cell lung cancer. After initiation of chemotherapy with etoposide and carboplatin ACTH and cortisol levels normalized and clinical symptoms impressively improved.
异位促肾上腺皮质激素（ACTH）综合征是低钾性高血压的一种罕见鉴别诊断。因小细胞肺癌导致异位ACTH综合征的患者预后较差。我们报告了一名68岁女性患者，她出现呼吸困难和低钾性高血压。内分泌检查结果符合因小细胞肺癌导致的异位ACTH综合征。在开始使用依托泊苷和顺铂进行化疗后，ACTH和皮质醇水平恢复正常，临床症状明显改善。
