Lee Joyce M, Okumura Megumi J, Freed Gary L, Menon Ram K, Davis Matthew M
Pediatric Endocrinology Unit, University of Michigan, Ann Arbor, Michigan, USA.
Diabetes Care. 2007 Dec;30(12):3035-9. doi: 10.2337/dc07-0769. Epub 2007 Aug 29.
The purpose of this study was to examine national trends in hospitalizations associated with diabetes for U.S. children and young adults.
The study included hospital discharges for individuals aged 0-29 years with a diagnosis of diabetes (250.xx) in the Nationwide Inpatient Sample (1993-2004). Outcomes were weighted, nationally representative estimates of the frequency of population-adjusted hospital discharges and hospital charges (2004 $U.S.).
Among individuals aged 0-29 years, population-adjusted rates of hospitalizations associated with diabetes over the 12-year period increased by 38% (99.1 of 100,000 in 1993 and 136.4 of 100,000 in 2004; P < 0.001 for curvilinear trend). Age-specific increases in annual hospitalizations for diabetes occurred primarily among individuals aged 20-24 years (152.6 of 100,000 in 1993 and 222.2 of 100,000 in 2004) and 25-29 years (224.9 of 100,000 in 1993 and 331.2 of 100,000 in 2004). Trends in hospitalizations among younger individuals showed no significant patterns. Hospitalization rates were consistently higher for females than for males, with a greater rate of increase for females (42%) than for males (29%) (P < 0.001). Inflation-adjusted total charges for diabetes hospitalizations increased 130%, from $1.05 billion in 1993 to $2.42 billion in 2004.
The number of young adults hospitalized with diabetes in the U.S. has increased significantly over the last decade. Sex-specific differences in hospitalization rates and trends in obesity among U.S. children may amplify future trends in diabetes hospitalizations and corresponding rapid growth in associated health care expenditures.
本研究旨在调查美国儿童和青年中与糖尿病相关的住院情况的全国趋势。
该研究纳入了全国住院患者样本(1993 - 2004年)中年龄在0 - 29岁且诊断为糖尿病(250.xx)的出院患者。结果是经加权的、具有全国代表性的人口调整后住院出院频率和住院费用估计值(2004年美元)。
在0 - 29岁的个体中,12年间与糖尿病相关的人口调整后住院率增加了38%(1993年每10万人中有99.1例,2004年每10万人中有136.4例;曲线趋势的P < 0.001)。糖尿病年度住院率的年龄特异性增加主要发生在20 - 24岁(1993年每10万人中有152.6例,2004年每10万人中有222.2例)和25 - 29岁(1993年每10万人中有224.9例,2004年每10万人中有331.2例)的个体中。较年轻个体的住院趋势无显著模式。女性的住院率始终高于男性,女性的增长率(42%)高于男性(29%)(P < 0.001)。经通胀调整后的糖尿病住院总费用增加了130%,从1993年的10.5亿美元增至2004年的24.2亿美元。
在过去十年中,美国因糖尿病住院的青年人数显著增加。美国儿童住院率的性别差异以及肥胖趋势可能会放大未来糖尿病住院的趋势以及相关医疗保健支出的相应快速增长。