Blessed G, Black S E, Butler T, Kay D W
MRC Neurochemical Pathology Unit, Newcastle General Hospital, Newcastle upon Tyne.
Br J Psychiatry. 1991 Aug;159:193-8. doi: 10.1192/bjp.159.2.193.
The performance of CAMCOG, the cognitive section of the CAMDEX, is compared in a non-random sample of 222 elderly people with diagnoses based on AGECAT and on DSM-III criteria, and with the MMSE and some short rating scales. With a cut-off point of 69/70 and AGECAT organic syndrome as the criterion, the sensitivity of CAMCOG was 97% and the specificity 91%. However, 21% of DSM-III diagnoses of dementia scored above this cut-off; these were mostly mild cases. The correlation between CAMCOG and MMSE scores was 0.87, and the advantage of CAMCOG may be more apparent in longitudinal studies. Multivariate analyses showed that CAMCOG scores are affected by age, sociocultural factors and hearing and visual deficits in addition to dementia, but not by depression. There was a suggestion that individual subsections are differentially affected.
在一个由222名老年人组成的非随机样本中,比较了基于AGECAT和DSM-III标准诊断的CAMDEX认知部分CAMCOG的表现,以及与简易精神状态检查表(MMSE)和一些简短评定量表的比较。以69/70的临界值和AGECAT器质性综合征为标准,CAMCOG的敏感性为97%,特异性为91%。然而,DSM-III痴呆诊断中有21%的得分高于此临界值;这些大多是轻度病例。CAMCOG与MMSE得分之间的相关性为0.87,CAMCOG的优势在纵向研究中可能更为明显。多变量分析表明,除痴呆外,CAMCOG得分还受年龄、社会文化因素以及听力和视力缺陷的影响,但不受抑郁症影响。有迹象表明各个子部分受到的影响有所不同。