Eckford S D, Abrams P
Department of Urology, Southmead Hospital, Bristol.
Br J Urol. 1991 Dec;68(6):586-9. doi: 10.1111/j.1464-410x.1991.tb15420.x.
A series of 25 women with genuine stress incontinence were treated by para-urethral injection of glutaraldehyde cross-linked collagen. The technique was simple and associated with few complications. Follow-up at 3 months revealed 20 patients (80%) to have been symptomatically improved or cured. An increase in urethral closure pressure together with a decrease in urine flow rate and increase in detrusor pressure was found post-operatively. The success rate was significantly higher (90%) in patients who had undergone previous surgery for urinary incontinence when compared with those who had had no previous surgery (73%).
对25例真性压力性尿失禁女性患者采用尿道旁注射戊二醛交联胶原蛋白进行治疗。该技术操作简单，并发症少。3个月的随访显示，20例患者（80%）症状得到改善或治愈。术后发现尿道闭合压升高，尿流率降低，逼尿肌压力升高。与未接受过尿失禁手术的患者（73%）相比，既往接受过尿失禁手术的患者成功率显著更高（90%）。
