表现为肢端红斑的坏死性小汗腺鳞状汗管化生。

Necrotizing eccrine squamous syringometaplasia presenting as acral erythema.

作者信息

Rongioletti F, Ballestrero A, Bogliolo F, Rebora A

机构信息

Department of Dermatology, University of Genoa, Italy.

出版信息

J Cutan Pathol. 1991 Dec;18(6):453-6. doi: 10.1111/j.1600-0560.1991.tb01384.x.

DOI:10.1111/j.1600-0560.1991.tb01384.x

PMID:1774355

Abstract

Acral erythema (AE) and eccrine squamous syringometaplasia (ESS) are distinctive clinico-pathological entities described in patients receiving chemotherapy for malignancies, mainly myelogenous leukemia. In no case of chemotherapy-induced AE have histopathologic changes of ESS been described. We report a patient with acute myelogenous leukemia who had typical AE due to cytarabine with histopathologic ESS. The latter findings in a case of AE may be a useful diagnostic clue for distinguishing chemotherapy-induced AE from palmo-plantar erythema of graft-vs-host reaction.

摘要

肢端红斑（AE）和小汗腺鳞状化生（ESS）是在接受恶性肿瘤化疗的患者中描述的独特临床病理实体，主要是骨髓性白血病。在化疗诱导的AE病例中，从未描述过ESS的组织病理学变化。我们报告了一名急性骨髓性白血病患者，其因阿糖胞苷出现典型的AE并伴有组织病理学上的ESS。在AE病例中的后一种发现可能是将化疗诱导的AE与移植物抗宿主反应的掌跖红斑区分开来的有用诊断线索。