Clausner B, Bolwin R, Frenzel J, Sander I, Rappsilber M, Eiselt M
Abteilung Neonatologie, Universitäts-Kinderklinik Jussuf Ibrahim, Jena.
Kinderarztl Prax. 1991 Dec;59(12):375-9.
The prognostic value of cranial ultrasound and EEG-monitoring for the developmental outcome at 1 year of age in 209 premature and full-term newborns was studied retrospectively. The first ultrasound examination was performed within the first three days of life. Further investigations were done depending on type of severity of the findings. The investigation was completed by EEG-monitoring in 41 patients. The infants were investigated for psychomotor development. 158 infants were found normally developed. Abnormal neonatal ultrasound findings were registered in 18.9% of them. Developmental retardation was observed in 46 infants. 54.3% of them had abnormal ultrasound findings. 2/3 of infants with neonatal major brain insults like IVH III-IV or leukomalacia showed serious neurological handicaps, whereas subependymal bleedings seem to be without influence onto the development. In contrast pathologic EEG's were of higher prognostic value. None of the infants with a abnormal EEG was developed normally.
回顾性研究了209例早产儿和足月儿头颅超声及脑电图监测对1岁时发育结局的预后价值。首次超声检查在出生后三天内进行。根据检查结果的严重程度类型进行进一步检查。41例患者通过脑电图监测完成检查。对婴儿进行心理运动发育检查。发现158例婴儿发育正常。其中18.9%有异常新生儿超声检查结果。46例婴儿观察到发育迟缓。其中54.3%有异常超声检查结果。2/3患有新生儿严重脑损伤如IVH III-IV级或脑白质软化的婴儿有严重神经功能障碍,而室管膜下出血似乎对发育无影响。相比之下,病理性脑电图具有更高的预后价值。脑电图异常的婴儿均无正常发育情况。