[阴囊外佩吉特病：79例报告]
[Extramammary Paget's disease of the scrotum: report of 79 cases].
作者信息
Xu Ke, Ding Qiang, Yu Jiang, Zheng Jie, Fang Zu-jun, Zhang Yuan-fang
机构信息
Department of Urology, Huashan Hospital, Fudan University, Shanghai, China.
出版信息
Zhonghua Zhong Liu Za Zhi. 2007 Apr;29(4):309-11.
OBJECTIVE
To investigate the clinicopathologic feature and treatment result as well as prognosis of Paget's disease of the scrotum.
METHODS
The data of 79 patients with Paget's disease of the scrotum confirmed pathologically from 1993 to 2004 were retrospectively analyzed. The median age of these patients was 62.3 years. The median duration of the disease was 3 years and 7 months. Locally extensive excision and intra-operative frozen section analysis of resection margin were performed in 78 patients. Inguinal and iliac radical lymphadenectomy was done in 7 patients with inguinal lymph node metastasis.
RESULTS
Local recurrence developed in 9 patients, and 3 patients died of the disease during follow-up.
CONCLUSION
The prognosis of Paget's disease of the scrotum after surgical resection is good. To highly watch out for the disease, to perform histological examination and surgical resection as early as possible are keys to control it successfully.
目的
探讨阴囊佩吉特病的临床病理特征、治疗效果及预后。
方法
回顾性分析1993年至2004年经病理确诊的79例阴囊佩吉特病患者的资料。这些患者的中位年龄为62.3岁。疾病的中位病程为3年7个月。78例患者行局部广泛切除及术中切缘冰冻切片分析。7例腹股沟淋巴结转移患者行腹股沟及髂骨根治性淋巴结清扫术。
结果
9例患者出现局部复发，3例患者在随访期间死于该病。
结论
阴囊佩吉特病手术切除后的预后良好。高度警惕该病，尽早进行组织学检查及手术切除是成功控制该病的关键。
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