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[阴囊佩吉特病的诊断与治疗:23例报告]

[Diagnosis and management of scrotal Paget's disease: report of 23 cases].

作者信息

Zhao Wei, Li Zhen-hua, Kong Chui-ze

机构信息

Department of Urology, The First Hospital Affiliated to China Medical University, Shenyang, Liaoning 110001, China.

出版信息

Zhonghua Nan Ke Xue. 2010 May;16(5):453-5.

Abstract

OBJECTIVE

To explore the clinical manifestation, management, recurrence factors and prognosis of scrotal Paget's disease.

METHODS

We retrospectively analyzed the clinical and pathological data of 23 cases of scrotal Paget's disease diagnosed and treated in our hospital from 1996 to 2008.

RESULTS

The disease was confined to one side of the scrotum in 15, and involved the whole scrotum and penis in 8 of the cases. Three patients showed enlarged inguinal lymph nodes in the same side, and 2 in both sides. All the cases were confirmed by biopsy and treated by surgery. Post-operative follow-up was conducted for 2-68 months, which revealed 5 cases of local recurrence and 1 case of death for systemic metastasis.

CONCLUSION

Biopsy is proved to be important for the early diagnosis of scrotal Paget's disease, and extended excision of local lesion is a preferred management.

摘要

目的

探讨阴囊佩吉特病的临床表现、治疗方法、复发因素及预后。

方法

回顾性分析1996年至2008年在我院诊断并治疗的23例阴囊佩吉特病患者的临床及病理资料。

结果

15例病变局限于阴囊一侧,8例累及整个阴囊及阴茎。3例患者同侧腹股沟淋巴结肿大,2例双侧肿大。所有病例均经活检确诊并接受手术治疗。术后随访2至68个月,发现5例局部复发,1例因全身转移死亡。

结论

活检对阴囊佩吉特病的早期诊断至关重要,局部病变扩大切除是首选治疗方法。

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