法属圭亚那患者的死亡风险因素：1996 - 2005年
Risk factors for death among patients in French Guiana: 1996-2005.
作者信息
Nacher M, Huber F, El Guedj M, Vaz T, Magnien C, Djossou F, Randrianjohany A, Alvarez F, Couppié P
机构信息
Centre d'Information et de Soins de l'Immunodéficience Humaine (CISIH) de Guyane, and Hôpital de Jour Adultes, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana.
出版信息
HIV Med. 2007 Oct;8(7):472-4. doi: 10.1111/j.1468-1293.2007.00492.x.
Risk factors for death in an HIV-infected cohort in French Guiana were studied in 1374 patients between 1996 and 2005. Of these patients, 48.5% were male and 76% were immigrants. Covariates were measured at the time of consultation. There were 223 deaths. Addictions [adjusted hazard ratio (HR)=13; 95% confidence interval (CI) 5.5-30.6; P<0.001], age>60 years (HR=1.5; 95% CI 0.9-2.5; P=0.13), male gender (HR=1.5; 95% CI 1.03-2.5; P=0.03) and CD4 count<50 cells/microL (HR=9.1; 95% CI 5.1-16.3; P<0.001) were independently associated with death. These results suggest that strategies promoting early diagnosis and better follow-up of addicted patients would have a significant impact on mortality.
1996年至2005年间，对法属圭亚那一个HIV感染队列中的1374名患者的死亡风险因素进行了研究。这些患者中，48.5%为男性，76%为移民。协变量在就诊时进行测量。共有223人死亡。成瘾（调整后风险比[HR]=13；95%置信区间[CI]5.5 - 30.6；P<0.001）、年龄>60岁（HR=1.5；95%CI 0.9 - 2.5；P=0.13）、男性（HR=1.5；95%CI 1.03 - 2.5；P=0.03）以及CD4细胞计数<50个/微升（HR=9.1；95%CI 5.1 - 16.3；P<0.001）与死亡独立相关。这些结果表明，促进对成瘾患者进行早期诊断和更好随访的策略将对死亡率产生重大影响。
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