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运动相关的自发性冠状动脉夹层:病例报告及文献综述

Exercise-related spontaneous coronary artery dissection: case report and literature review.

作者信息

Kalaga Ravishankar V, Malik Amyn, Thompson Paul D

机构信息

Division of Cardiology, Henry Low Heart Center, Hartford Hospital, Hartford, CT 06102, USA.

出版信息

Med Sci Sports Exerc. 2007 Aug;39(8):1218-20. doi: 10.1249/mss.0b013e318060114f.

Abstract

BACKGROUND

Spontaneous coronary artery dissection is a rare cause of acute cardiac events and occurs most frequently in the peripartum period. Coronary artery dissection related to exercise is even more unusual, with only a few cases reported in the literature. We report a case of acute coronary artery dissection related to exercise in a 17-yr-old high school athlete, and we review the available literature on exercise-related coronary dissection.

METHODS

We performed a PubMed literature search using the search terms exercise, sports, spontaneous coronary dissection, and athletics. We found seven cases of spontaneous coronary artery dissection that had occurred during intense physical exercise. Vigorous exercise can provoke acute ischemic events, but such events occur primarily in adults with atherosclerotic disease. Many of the cases reported as spontaneous coronary artery dissection are more likely atherosclerotic plaque rupture, in which cases they are not truly spontaneous. Because spontaneous coronary dissection is so rare, there are no available recommendations on how to manage young athletes with this condition. We permitted this athlete to return to limited competition, without data to support either a total restriction or even a limited restriction, with the written understanding that a recurrent event is possible but probably unlikely. In summary, spontaneous coronary artery dissection should be considered in young individuals presenting with exercise-related acute ischemic cardiac events.

摘要

背景

自发性冠状动脉夹层是急性心脏事件的罕见病因,最常发生于围产期。与运动相关的冠状动脉夹层更为罕见,文献中仅有少数病例报道。我们报告一例17岁高中运动员与运动相关的急性冠状动脉夹层病例,并回顾运动相关冠状动脉夹层的现有文献。

方法

我们使用“运动”“体育”“自发性冠状动脉夹层”和“田径运动”等检索词在PubMed数据库进行文献检索。我们发现7例在剧烈体育锻炼期间发生的自发性冠状动脉夹层病例。剧烈运动可引发急性缺血事件,但此类事件主要发生于患有动脉粥样硬化疾病的成年人。许多被报道为自发性冠状动脉夹层的病例更可能是动脉粥样硬化斑块破裂,在这种情况下并非真正的自发性。由于自发性冠状动脉夹层非常罕见,对于如何处理患有这种疾病的年轻运动员尚无可用建议。我们允许该运动员恢复有限的比赛,在没有数据支持完全限制甚至有限制的情况下,书面告知其可能再次发生事件,但可能性不大。总之,对于出现与运动相关急性缺血性心脏事件的年轻人,应考虑自发性冠状动脉夹层。

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